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The Capital Region of Denmark - a part of Copenhagen University Hospital
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First experiences from Copenhagen with paediatric single photon emission computed tomography/computed tomography

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  1. Improving quantitative dosimetry in (177)Lu-DOTATATE SPECT by energy window-based scatter corrections

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  2. Calibrated image-derived input functions for the determination of the metabolic uptake rate of glucose with [18F]-FDG PET

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  3. Determination of kidney function with 99mTc-DTPA renography using a dual-head camera

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  4. A comparison of different energy window subtraction methods to correct for scatter and downscatter in I-123 SPECT imaging

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  1. Recurrence and survival rates in node negative patients after sentinel node biopsy for early-stage vulva cancer - A nationwide study

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  2. Near-infrared fluorescence imaging improves the nodal yield in neck dissection in oral cavity cancer - A randomized study

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  3. Inhalatortyper og inhalationsteknik ved behandling af astma og kronisk obstruktiv lungesygdom

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  4. Early Postoperative 18F-FET PET/MRI for Pediatric Brain and Spinal Cord Tumors

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OBJECTIVE: This study evaluates the diagnostic value of single photon emission computed tomographic (SPECT)/multislice computed tomographic (MSCT) fusion images compared with planar scintigraphy in children. METHODS: Fifteen children [eight girls, mean age 13 years (range 2-17 years)] who were examined in the SPECT/16-MSCT scanner at the Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet were included. The studies and clinical indications were eight Tc-hydroxymethane diphosphonate bone scintigraphies (three bone abnormalities, three osteomyelitis, two bone tumours), one bone scintigraphy combined with In-labelled leukocyte study (osteomyelitis), three I-meta-iodobenzylguanidine scintigraphies (neuroblastoma), three In-octreotide scintigraphies (two carcinoid tumours, one Langerhans cell histiocytosis) and one Tc-dimercaptosuccinic acid scintigraphy (suspected renal transplant infarction). At the evaluation of the planar scans, the decision to perform a SPECT/16-MSCT scan was taken. A specialist in nuclear medicine read the SPECT scans and the CT scans were, if performed as high resolution or when in doubt, read by the specialist in radiology, followed by a simultaneous reading. We categorized the additional information gained from the SPECT/MSCT scan into three groups: (i) structural information gained from the CT scan, (ii) additional nuclear medicine information gained from the SPECT scan and (iii) information used for biopsy guidance. Use of a CT scan of diagnostic quality was only allowed (n=1) after referral from the clinicians, and read in collaboration with the specialist in radiology. RESULTS: Fourteen of the 15 planar scans gained additional structural information from SPECT/CT. Twelve of 15 planar scans gained additional nuclear medicine information. Six studies gained specific information for biopsy guidance. CONCLUSION: SPECT/CT provided additional information in all cases. SPECT/CT in children seems to be a most valuable tool and it increases the certainty of the diagnostic work-up.
Original languageEnglish
JournalNuclear Medicine Communications
Volume32
Issue number5
Pages (from-to)356-362
ISSN0143-3636
DOIs
Publication statusPublished - 4 Mar 2011

ID: 31032009