Final infarct size measured by cardiovascular magnetic resonance in patients with ST elevation myocardial infarction predicts long-term clinical outcome: an observational study

Jacob Lønborg; Niels Vejlstrup; Henning Kelbæk; Lene Holmvang; Erik Jørgensen; Steffen Helqvist; Kari Saunamäki; Kiril Aleksov Ahtarovski; Hans Erik Bøtker; Won Yong Kim; Peter Clemmensen; Thomas Engstrøm

doi:10.1093/ehjci/jes271

Final infarct size measured by cardiovascular magnetic resonance in patients with ST elevation myocardial infarction predicts long-term clinical outcome: an observational study

Jacob Lønborg, Niels Vejlstrup, Henning Kelbæk, Lene Holmvang, Erik Jørgensen, Steffen Helqvist, Kari Saunamäki, Kiril Aleksov Ahtarovski, Hans Erik Bøtker, Won Yong Kim, Peter Clemmensen, Thomas Engstrøm

118 Citations (Scopus)

Abstract

AIMS: Tailored heart failure treatment and risk assessment in patients following ST-segment elevation myocardial infarction (STEMI) is mainly based on the assessment of the left ventricular (LV) ejection fraction (EF). Assessment of the final infarct size in addition to the LVEF may improve the prognostic evaluation. To evaluate the prognostic importance of the final infarct size measured by cardiovascular magnetic resonance (CMR) in patients with STEMI. METHODS AND RESULTS: In an observational study the final infarct size was measured by late gadolinium enhancement CMR 3 months after initial admission in 309 patients with STEMI. The clinical endpoint was a composite of all-cause mortality and admission for heart failure. During the follow-up period of median 807 days (IQR: 669-1117) 35 events (5 non-cardiac deaths, 3 cardiac deaths, and 27 admissions for heart failure) were recorded. Patients with a final infarct size ≥median had significantly higher event rates than patients with a final infarct size

Original language	English
Journal	European heart journal cardiovascular Imaging
Volume	14
Issue number	4
Pages (from-to)	387-95
DOIs	https://doi.org/10.1093/ehjci/jes271
Publication status	Published - 2013

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Lønborg, J., Vejlstrup, N., Kelbæk, H., Holmvang, L., Jørgensen, E., Helqvist, S., Saunamäki, K., Ahtarovski, K. A., Bøtker, H. E., Kim, W. Y., Clemmensen, P., & Engstrøm, T. (2013). Final infarct size measured by cardiovascular magnetic resonance in patients with ST elevation myocardial infarction predicts long-term clinical outcome: an observational study. European heart journal cardiovascular Imaging, 14(4), 387-95. https://doi.org/10.1093/ehjci/jes271

Final infarct size measured by cardiovascular magnetic resonance in patients with ST elevation myocardial infarction predicts long-term clinical outcome: an observational study. / Lønborg, Jacob ; Vejlstrup, Niels; Kelbæk, Henning et al.
In: European heart journal cardiovascular Imaging, Vol. 14, No. 4, 2013, p. 387-95.

Research output: Contribution to journal › Journal article › Research › peer-review

Lønborg, J , Vejlstrup, N, Kelbæk, H, Holmvang, L , Jørgensen, E , Helqvist, S, Saunamäki, K, Ahtarovski, KA, Bøtker, HE, Kim, WY, Clemmensen, P & Engstrøm, T 2013, 'Final infarct size measured by cardiovascular magnetic resonance in patients with ST elevation myocardial infarction predicts long-term clinical outcome: an observational study', European heart journal cardiovascular Imaging, vol. 14, no. 4, pp. 387-95. https://doi.org/10.1093/ehjci/jes271

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title = "Final infarct size measured by cardiovascular magnetic resonance in patients with ST elevation myocardial infarction predicts long-term clinical outcome: an observational study",

abstract = "AIMS: Tailored heart failure treatment and risk assessment in patients following ST-segment elevation myocardial infarction (STEMI) is mainly based on the assessment of the left ventricular (LV) ejection fraction (EF). Assessment of the final infarct size in addition to the LVEF may improve the prognostic evaluation. To evaluate the prognostic importance of the final infarct size measured by cardiovascular magnetic resonance (CMR) in patients with STEMI. METHODS AND RESULTS: In an observational study the final infarct size was measured by late gadolinium enhancement CMR 3 months after initial admission in 309 patients with STEMI. The clinical endpoint was a composite of all-cause mortality and admission for heart failure. During the follow-up period of median 807 days (IQR: 669-1117) 35 events (5 non-cardiac deaths, 3 cardiac deaths, and 27 admissions for heart failure) were recorded. Patients with a final infarct size ≥median had significantly higher event rates than patients with a final infarct size ",

author = "Jacob L{\o}nborg and Niels Vejlstrup and Henning Kelb{\ae}k and Lene Holmvang and Erik J{\o}rgensen and Steffen Helqvist and Kari Saunam{\"a}ki and Ahtarovski, {Kiril Aleksov} and B{\o}tker, {Hans Erik} and Kim, {Won Yong} and Peter Clemmensen and Thomas Engstr{\o}m",

year = "2013",

doi = "10.1093/ehjci/jes271",

language = "English",

volume = "14",

pages = "387--95",

journal = "European heart journal cardiovascular Imaging",

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T1 - Final infarct size measured by cardiovascular magnetic resonance in patients with ST elevation myocardial infarction predicts long-term clinical outcome

T2 - an observational study

AU - Lønborg, Jacob

AU - Vejlstrup, Niels

AU - Kelbæk, Henning

AU - Holmvang, Lene

AU - Jørgensen, Erik

AU - Helqvist, Steffen

AU - Saunamäki, Kari

AU - Ahtarovski, Kiril Aleksov

AU - Bøtker, Hans Erik

AU - Kim, Won Yong

AU - Clemmensen, Peter

AU - Engstrøm, Thomas

PY - 2013

Y1 - 2013

N2 - AIMS: Tailored heart failure treatment and risk assessment in patients following ST-segment elevation myocardial infarction (STEMI) is mainly based on the assessment of the left ventricular (LV) ejection fraction (EF). Assessment of the final infarct size in addition to the LVEF may improve the prognostic evaluation. To evaluate the prognostic importance of the final infarct size measured by cardiovascular magnetic resonance (CMR) in patients with STEMI. METHODS AND RESULTS: In an observational study the final infarct size was measured by late gadolinium enhancement CMR 3 months after initial admission in 309 patients with STEMI. The clinical endpoint was a composite of all-cause mortality and admission for heart failure. During the follow-up period of median 807 days (IQR: 669-1117) 35 events (5 non-cardiac deaths, 3 cardiac deaths, and 27 admissions for heart failure) were recorded. Patients with a final infarct size ≥median had significantly higher event rates than patients with a final infarct size

AB - AIMS: Tailored heart failure treatment and risk assessment in patients following ST-segment elevation myocardial infarction (STEMI) is mainly based on the assessment of the left ventricular (LV) ejection fraction (EF). Assessment of the final infarct size in addition to the LVEF may improve the prognostic evaluation. To evaluate the prognostic importance of the final infarct size measured by cardiovascular magnetic resonance (CMR) in patients with STEMI. METHODS AND RESULTS: In an observational study the final infarct size was measured by late gadolinium enhancement CMR 3 months after initial admission in 309 patients with STEMI. The clinical endpoint was a composite of all-cause mortality and admission for heart failure. During the follow-up period of median 807 days (IQR: 669-1117) 35 events (5 non-cardiac deaths, 3 cardiac deaths, and 27 admissions for heart failure) were recorded. Patients with a final infarct size ≥median had significantly higher event rates than patients with a final infarct size

U2 - 10.1093/ehjci/jes271

DO - 10.1093/ehjci/jes271

M3 - Journal article

C2 - 23178864

SN - 1532-2114

SN - 2047-2412

VL - 14

SP - 387

EP - 395

JO - European heart journal cardiovascular Imaging

JF - European heart journal cardiovascular Imaging

IS - 4

ER -

Final infarct size measured by cardiovascular magnetic resonance in patients with ST elevation myocardial infarction predicts long-term clinical outcome: an observational study

Abstract

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