Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Fertility in cancer patients after cryopreservation of one ovary

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Meditation and mindfulness reduce perceived stress in women with recurrent pregnancy loss: a randomized controlled trial

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Stress and depression among women and men who have experienced recurrent pregnancy loss: focusing on both sexes

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Empathetic application of machine learning may address appropriate utilization of ART

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Futures and fears in the freezer: Danish women's experiences with ovarian tissue cryopreservation and transplantation

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. The reproductive microbiome - clinical practice recommendations for fertility specialists

    Research output: Contribution to journalReviewResearchpeer-review

  1. A systematic review and meta-analysis on the association between ICSI and chromosome abnormalities

    Research output: Contribution to journalReviewResearchpeer-review

  2. Parenthood among men diagnosed with cancer in childhood and early adulthood: trends over time in a Danish national cohort

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Proteome of fluid from human ovarian small antral follicles reveals insights in folliculogenesis and oocyte maturation

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. N-acetylcysteine protects ovarian follicles from ischemia-reperfusion injury in xenotransplanted human ovarian tissue

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
This questionnaire study describes the fertility and ovarian function in 143 adult female cancer survivors with only one ovary due to cryopreservation of the other. The women were asked about their ovarian function (as defined by the presence of a spontaneous menstrual cycle), pregnancies and their outcome. The mean follow-up time was 58months after cryopreservation (range 24-129months). The risk of premature ovarian failure was high in the group of patients with leukaemia (13/15; 87%) but low in the breast cancer group (5/54; 9%). Fifty-seven women had actively tried to become pregnant after end of treatment; of these, 41 women obtained a total of 68 pregnancies resulting in 45 live births and five ongoing pregnancies, 15 spontaneous abortions, one ectopic pregnancy and two elective abortions. In the remaining 86 women without a pregnancy wish, there had been five elective abortions. Ninety-three per cent of the pregnancies were after natural conception and only four cases were a result of fertility treatment. The overall risk of premature ovarian failure was low (22%). Patients who retain their ovarian function after treatment of a malignant disease have a good chance of becoming pregnant.
Original languageEnglish
JournalReproductive BioMedicine Online
Volume26
Issue number3
Pages (from-to)272-9
Number of pages8
ISSN1472-6483
DOIs
Publication statusPublished - Mar 2013

    Research areas

  • Attitude, Breast Neoplasms, Cryopreservation, Female, Fertility, Fertility Preservation, Humans, Leukemia, Neoplasms, Ovary, Pregnancy, Pregnancy Outcome, Pregnancy Rate, Primary Ovarian Insufficiency, Risk Assessment, Survivors

ID: 40395860