Fenómenos de despolarización cortical propagada en los pacientes con lesiones cerebrales traumáticas e isquémicas. Resultados de un estudio piloto

M Sueiras; J Sahuquillo; B García-López; Á Sánchez-Guerrero; M A Poca; E Santamarina; M Riveiro; M Fabricius; A J Strong

doi:10.1016/j.medin.2013.09.008

Fenómenos de despolarización cortical propagada en los pacientes con lesiones cerebrales traumáticas e isquémicas. Resultados de un estudio piloto

Translated title of the contribution: Cortical spreading depolarization phenomena in patients with traumatic and ischemic brain injuries. Results of a pilot study

M Sueiras, J Sahuquillo, B García-López, Á Sánchez-Guerrero, M A Poca, E Santamarina, M Riveiro, M Fabricius, A J Strong

1 Citation (Scopus)

Abstract

OBJECTIVES: To determine the frequency and duration of cortical spreading depolarization (CSD) and CSD-like episodes in patients with traumatic brain injury (TBI) and malignant middle cerebral artery infarction (MMCAI) requiring craniotomy.

DESIGN: A descriptive observational study was carried out during 19 months.

SETTING: Neurocritical patients.

PATIENTS: Sixteen patients were included: 9 with MMCAI and 7 with moderate or severe TBI, requiring surgical treatment.

INTERVENTIONS: A 6-electrode subdural electrocorticographic (ECoG) strip was placed onto the perilesional cortex.

MAIN VARIABLES OF INTEREST: An analysis was made of the time profile and the number and duration of CSD and CSD-like episodes recorded from the ECoGs.

RESULTS: Of the 16 patients enrolled, 9 presented episodes of CSD or CSD-like phenomena, of highly variable frequency and duration.

CONCLUSIONS: Episodes of CSD and CSD-like phenomena are frequently detected in the ischemic penumbra and/or traumatic cortical regions of patients with MMCAI who require decompressive craniectomy or of patients with contusional TBI.

Translated title of the contribution	Cortical spreading depolarization phenomena in patients with traumatic and ischemic brain injuries. Results of a pilot study
Original language	Spanish
Journal	Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias
Volume	38
Issue number	7
Pages (from-to)	413-21
Number of pages	9
DOIs	https://doi.org/10.1016/j.medin.2013.09.008
Publication status	Published - Oct 2014

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Sueiras, M., Sahuquillo, J., García-López, B., Sánchez-Guerrero, Á., Poca, M. A., Santamarina, E., Riveiro, M., Fabricius, M., & Strong, A. J. (2014). Fenómenos de despolarización cortical propagada en los pacientes con lesiones cerebrales traumáticas e isquémicas. Resultados de un estudio piloto. Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias, 38(7), 413-21. https://doi.org/10.1016/j.medin.2013.09.008

Fenómenos de despolarización cortical propagada en los pacientes con lesiones cerebrales traumáticas e isquémicas. Resultados de un estudio piloto. / Sueiras, M; Sahuquillo, J; García-López, B et al.
In: Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias, Vol. 38, No. 7, 10.2014, p. 413-21.

Research output: Contribution to journal › Journal article › Research › peer-review

Sueiras, M, Sahuquillo, J, García-López, B, Sánchez-Guerrero, Á, Poca, MA, Santamarina, E, Riveiro, M, Fabricius, M & Strong, AJ 2014, 'Fenómenos de despolarización cortical propagada en los pacientes con lesiones cerebrales traumáticas e isquémicas. Resultados de un estudio piloto', Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias, vol. 38, no. 7, pp. 413-21. https://doi.org/10.1016/j.medin.2013.09.008

Sueiras M, Sahuquillo J, García-López B, Sánchez-Guerrero Á, Poca MA, Santamarina E et al. Fenómenos de despolarización cortical propagada en los pacientes con lesiones cerebrales traumáticas e isquémicas. Resultados de un estudio piloto. Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias. 2014 Oct;38(7):413-21. doi: 10.1016/j.medin.2013.09.008

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abstract = "OBJECTIVES: To determine the frequency and duration of cortical spreading depolarization (CSD) and CSD-like episodes in patients with traumatic brain injury (TBI) and malignant middle cerebral artery infarction (MMCAI) requiring craniotomy.DESIGN: A descriptive observational study was carried out during 19 months.SETTING: Neurocritical patients.PATIENTS: Sixteen patients were included: 9 with MMCAI and 7 with moderate or severe TBI, requiring surgical treatment.INTERVENTIONS: A 6-electrode subdural electrocorticographic (ECoG) strip was placed onto the perilesional cortex.MAIN VARIABLES OF INTEREST: An analysis was made of the time profile and the number and duration of CSD and CSD-like episodes recorded from the ECoGs.RESULTS: Of the 16 patients enrolled, 9 presented episodes of CSD or CSD-like phenomena, of highly variable frequency and duration.CONCLUSIONS: Episodes of CSD and CSD-like phenomena are frequently detected in the ischemic penumbra and/or traumatic cortical regions of patients with MMCAI who require decompressive craniectomy or of patients with contusional TBI.",

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AU - Sueiras, M

AU - Sahuquillo, J

AU - García-López, B

AU - Sánchez-Guerrero, Á

AU - Poca, M A

AU - Santamarina, E

AU - Riveiro, M

AU - Fabricius, M

AU - Strong, A J

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N2 - OBJECTIVES: To determine the frequency and duration of cortical spreading depolarization (CSD) and CSD-like episodes in patients with traumatic brain injury (TBI) and malignant middle cerebral artery infarction (MMCAI) requiring craniotomy.DESIGN: A descriptive observational study was carried out during 19 months.SETTING: Neurocritical patients.PATIENTS: Sixteen patients were included: 9 with MMCAI and 7 with moderate or severe TBI, requiring surgical treatment.INTERVENTIONS: A 6-electrode subdural electrocorticographic (ECoG) strip was placed onto the perilesional cortex.MAIN VARIABLES OF INTEREST: An analysis was made of the time profile and the number and duration of CSD and CSD-like episodes recorded from the ECoGs.RESULTS: Of the 16 patients enrolled, 9 presented episodes of CSD or CSD-like phenomena, of highly variable frequency and duration.CONCLUSIONS: Episodes of CSD and CSD-like phenomena are frequently detected in the ischemic penumbra and/or traumatic cortical regions of patients with MMCAI who require decompressive craniectomy or of patients with contusional TBI.

AB - OBJECTIVES: To determine the frequency and duration of cortical spreading depolarization (CSD) and CSD-like episodes in patients with traumatic brain injury (TBI) and malignant middle cerebral artery infarction (MMCAI) requiring craniotomy.DESIGN: A descriptive observational study was carried out during 19 months.SETTING: Neurocritical patients.PATIENTS: Sixteen patients were included: 9 with MMCAI and 7 with moderate or severe TBI, requiring surgical treatment.INTERVENTIONS: A 6-electrode subdural electrocorticographic (ECoG) strip was placed onto the perilesional cortex.MAIN VARIABLES OF INTEREST: An analysis was made of the time profile and the number and duration of CSD and CSD-like episodes recorded from the ECoGs.RESULTS: Of the 16 patients enrolled, 9 presented episodes of CSD or CSD-like phenomena, of highly variable frequency and duration.CONCLUSIONS: Episodes of CSD and CSD-like phenomena are frequently detected in the ischemic penumbra and/or traumatic cortical regions of patients with MMCAI who require decompressive craniectomy or of patients with contusional TBI.

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DO - 10.1016/j.medin.2013.09.008

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JO - Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias

JF - Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias

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Fenómenos de despolarización cortical propagada en los pacientes con lesiones cerebrales traumáticas e isquémicas. Resultados de un estudio piloto

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