Feasibility of Time-Restricted Eating in the Treatment of Type 2 Diabetes – the RESET2 Pilot Study

Abstract

Background: Time-restricted eating (TRE) is a type of intermittent fasting reducing the interval for eating and drinking without other dietary restrictions.

Aim: To investigate the feasibility of a 12-week 10-h TRE-based intervention targeting people with type 2 diabetes (T2D), including the participants’ needs and barriers when following TRE.

Methods: In this single-arm pilot study, 10 men and 10 women with T2D (mean HbA1c: 61.5 mmol/mol and T2D duration: 15 years) followed a 12-week intervention co-created with people with T2D, their relatives and healthcare professionals (HCP). First, participants followed 8 weeks of strict TRE with a self-selected, fixed 10-h eating window (EW) to obtain lived experiences with TRE. This was followed by a 4-week TRE period with individually selected adjustments such as occasional rescheduling of EW, calorie-free beverages outside the EW, peer-support sessions, and phone calls with HCP. The individual EW and adjustments were planned during 1-hour meetings with an HCP at baseline and after 8 weeks. Body weight and HbA1c were measured at baseline and after 12 weeks. Qualitative interviews were conducted at baseline, after 8 and 12 weeks.

Results: Nineteen participants (median age: 68 years, mean body weight: 105.8 kg, and BMI: 36.7 kg/m2) completed the study. Body weight (-2.0 kg (95% CI: -2.9, -1.1), p
Conclusions: We found that 12-weeks of TRE was feasible and well-tolerated and may improve glycemic control and body weight in individuals with T2D.
Original languageEnglish
Article number1613-P
JournalDiabetes
Volume72
Issue numbersuppl 1
ISSN0012-1797
DOIs
Publication statusPublished - 25 Jun 2023
EventAmerican Diabetes Association's 83nd Scientific Session, ADA - San Diego, United States
Duration: 23 Jun 202326 Jun 2023

Conference

ConferenceAmerican Diabetes Association's 83nd Scientific Session, ADA
LocationSan Diego
Country/TerritoryUnited States
Period23/06/202326/06/2023

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