FDG PET/CT imaging in canine cancer patients

Anders Hansen, Fintan McEvoy, Svend A Engelholm, Ian Law, Annemarie Thuri Kristensen

49 Citations (Scopus)

Abstract

2-Deoxy-2-[¹⁸F]fluoro-D-glucose positron emission tomography/computed tomography (FDG PET/CT) is becoming increasingly available as an imaging modality in veterinary medicine. The purpose of this study was to report semiquantitative standard uptake values (SUV) of malignant and nonmalignant tissues and organs in canine cancer patients. FDG PET/CT was performed in 14 dogs including, nine mesenchymal tumors, four carcinomas, and one incompletely excised mast cell tumor. A generally higher FDG uptake was observed in carcinomas relative to sarcomas. Maximum SUV of carcinomas ranged from 7.6 to 27.0, and for sarcomas from 2.0 to 10.6. The FDG SUV of several organs and tissues, including regional brain uptake is reported, to serve as a reference for future FDG PET studies in canine cancer patients. Several potential pitfalls have been recognized in interpretation of FDG PET images of human patients, a number of these were also observed in this study.
Original languageEnglish
JournalVeterinary Radiology & Ultrasound
Volume52
Issue number2
Pages (from-to)201-6
Number of pages6
ISSN1058-8183
DOIs
Publication statusPublished - 2011

Keywords

  • Animals
  • Brain
  • Dog Diseases
  • Dogs
  • Fluorodeoxyglucose F18
  • Heart
  • Kidney Cortex
  • Liver
  • Muscle, Skeletal
  • Neoplasms
  • Positron-Emission Tomography
  • Reference Values
  • Spleen
  • Submandibular Gland
  • Tomography, X-Ray Computed

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