Fatal rupture of the spleen caused by infiltration of T-cell lymphoma

I Schiødt, E Duun, T K Fischer, A P Christiansen, E Ralfkiaer

    Abstract

    Pathological or spontaneous rupture of the spleen has been described in a variety of diseases affecting the spleen, with infections being cited as the cause in most cases. In hematological malignancies it is a rare event, despite the frequent involvement of the spleen in these diseases. It has, however, been described in patients with acute and chronic leukemia, Hodgkin's disease, non-Hodgkin's lymphoma of B-cell origin, mycosis fungoides, and so-called histiocytic lymphoma. Here, we present a fatal case of splenic rupture caused by infiltration of a peripheral T-cell lymphoma, unspecified according to the REAL classification. The importance of a correct diagnosis and fast surgery is emphasized.

    Original languageEnglish
    JournalAnnals of Hematology
    Volume79
    Issue number3
    Pages (from-to)158-60
    Number of pages3
    ISSN0939-5555
    Publication statusPublished - Mar 2000

    Keywords

    • Fatal Outcome
    • Humans
    • Lymphoma, T-Cell/pathology
    • Male
    • Middle Aged
    • Neoplasm Invasiveness
    • Spleen/pathology
    • Splenic Rupture/etiology

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