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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Facial nerve function after vestibular schwannoma surgery following failed conservative management

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  3. natural history of vestibular schwannoma

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BACKGROUND:: As only a limited proportion of vestibular schwannomas display growth following diagnosis, an increasing number of patients are managed conservatively. Tumor growth during "wait and scan" may, however, necessitate surgery. In these cases, increased tumor size is likely to increase the risk of impaired facial nerve function post-surgery. OBJECTIVE:: To compare facial nerve function in patients operated soon after diagnosis with patients allocated to conservative management, and the subgroup of these who later had surgery due to tumor growth. METHODS:: 1378 consecutive patients diagnosed with a vestibular schwannoma 20mm extrameatal or smaller were included. 419 patients were operated soon after diagnosis and 959 patients were initially managed conservatively. In the latter group, 161 patients were subsequently operated due to tumor growth. RESULTS:: All conservatively managed patients had normal facial nerve function at the end of observation. Good facial nerve outcome was found in 87 % of patients operated at diagnosis, and in 84 % of patients operated after established tumor growth. For the subgroup of small extrameatal tumors this difference was significant. Pooling all patients allocated primarily to conservative management, good facial function was found in 97%, which was significantly better than the result for primary operation (87%). CONCLUSION:: Overall, conservative management of small to medium-sized vestibular schwannomas is the best option with regard to preservation of the facial nerve function. Tumor growth during observation is found in only a minor proportion of the patients, and in these cases surgery or irradiation should be performed immediately.
Original languageEnglish
JournalNeurosurgery (Baltimore)
Volume70
Issue number2
Pages (from-to)278-282, discussion 282
ISSN0148-396X
DOIs
Publication statusPublished - 2012

ID: 33175323