Exploring protective and risk factors in the home environment in high-risk families - results from the Danish High Risk and Resilience Study-VIA 7

Anne Amalie Elgaard Thorup, Ditte Lou Gantriis, Aja Neergaard Greve, Maria Toft Henriksen, Kate Kold Zahle, Henriette Stadsgaard, Ditte Ellersgaard, Birgitte Klee Burton, Camilla Jerlang Christiani, Katrine Spang, Nicoline Hemager, Jens Richardt Møllegaard Jepsen, Kerstin J Plessen, Merete Nordentoft, Ole Mors, Vibeke Bliksted

4 Citations (Scopus)

Abstract

BACKGROUND: Exposure to inadequate home environment may put the healthy development of familial high-risk children at risk. This study aimed to investigate associations between risk factors and an adequate home environment of children having a parent diagnosed with schizophrenia or bipolar disorder.

METHODS: From a cohort of 522 children, data from 463 7-year-old children was included. Of these 172 children had familial risk for schizophrenia, 109 children had familial risk for bipolar disorder, and 190 were population-based controls. As part of a comprehensive battery, all participants were assessed with the Middle Childhood-Home Observation for Measurement of the Environment Inventory (MC-HOME Inventory) measuring the quality of the home environment.

RESULTS: When analyzing all families together, we found that having a parent diagnosed with schizophrenia would have a negative impact on the home environment (ß = -1.08; 95% CI (-2.16;-0.01); p = 0.05), while familial risk for bipolar disorder did not show significant predictive value. Being a single caregiver and child having experienced severe life events from ages 4 to 7 showed significant negative impact, while child having a mental illness diagnosis did not. Being a female caregiver, good social functioning of the caregiver, high child IQ and not being a single caregiver were found to predict positive values for the home environment. We found similar results when analyzing caregivers with and without a diagnosis separately.

CONCLUSIONS: Knowledge of what predicts good home environment should be used to inform development of early interventions for families at risk.

Original languageEnglish
Article number100
JournalBMC Psychiatry
Volume22
Issue number1
ISSN1471-244X
DOIs
Publication statusPublished - Dec 2022

Keywords

  • Bipolar disorder
  • Familial high-risk
  • Home environment
  • Risk factors
  • Schizophrenia

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