Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Experimental knee pain reduces muscle strength

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Modulation of Itch by Conditioning Itch and Pain Stimulation in Healthy Humans

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The relationship between sensory loss and persistent pain 1 year after breast cancer surgery

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Conditioned Pain Modulation and Pressure Pain Sensitivity in the Adult Danish General Population: The DanFunD Study

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Weight-bearing MRI of the Lumbar Spine: Spinal Stenosis and Spondylolisthesis

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Weight-bearing MRI of the Lumbar Spine: Technical Aspects

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
Pain is the principal symptom in knee pathologies and reduced muscle strength is a common observation among knee patients. However, the relationship between knee joint pain and muscle strength remains to be clarified. This study aimed at investigating the changes in knee muscle strength following experimental knee pain in healthy volunteers, and if these changes were associated with the pain intensities. In a crossover study, 18 healthy subjects were tested on 2 different days. Using an isokinetic dynamometer, maximal muscle strength in knee extension and flexion was measured at angular velocities 0, 60, 120, and 180 degrees/second, before, during, and after experimental pain induced by injections of hypertonic saline into the infrapatellar fat pad. On a separate day, isotonic saline injections were used as control condition. The pain intensity was assessed on a 0- to 100-mm visual analogue scale. Knee pain reduced the muscle strength by 5 to 15% compared to the control conditions (P <.001) in both knee extension and flexion at all angular velocities. The reduction in muscle strength was positively correlated to the pain intensity. Experimental knee pain significantly reduced knee extension and flexion muscle strength indicating a generalized muscle inhibition augmented by higher pain intensities. PERSPECTIVE: This study showed that knee joint pain has a significant impact on muscle function. The findings provide evidence of a direct inhibition of muscle function by joint pain, implying that rehabilitative strengthening exercises may be antagonized by joint pain.
Original languageEnglish
JournalJournal of Pain
Volume12
Issue number4
Pages (from-to)460-7
Number of pages8
ISSN1526-5900
DOIs
Publication statusPublished - 1 Apr 2011

ID: 32354367