TY - JOUR
T1 - Exercise training normalizes skeletal muscle vascular endothelial growth factor levels in patients with essential hypertension
AU - Hansen, Ane Håkansson
AU - Nielsen, Jens
AU - Saltin, Bengt
AU - Hellsten, Ylva
PY - 2010/6/1
Y1 - 2010/6/1
N2 - Vascular endothelial growth factor (VEGF) protein and capillarization were determined in muscle vastus lateralis biopsy samples in individuals with essential hypertension (n = 10) and normotensive controls (n = 10). The hypertensive individuals performed exercise training for 16 weeks. Muscle samples as well as muscle microdialysis fluid samples were obtained at rest, during and after an acute exercise bout, performed prior to and after the training period, for the determination of muscle VEGF levels, VEGF release, endothelial cell proliferative effect and capillarization.
AB - Vascular endothelial growth factor (VEGF) protein and capillarization were determined in muscle vastus lateralis biopsy samples in individuals with essential hypertension (n = 10) and normotensive controls (n = 10). The hypertensive individuals performed exercise training for 16 weeks. Muscle samples as well as muscle microdialysis fluid samples were obtained at rest, during and after an acute exercise bout, performed prior to and after the training period, for the determination of muscle VEGF levels, VEGF release, endothelial cell proliferative effect and capillarization.
U2 - 10.1097/HJH.0b013e3283379120
DO - 10.1097/HJH.0b013e3283379120
M3 - Journal article
C2 - 20179634
VL - 28
SP - 1176
EP - 1185
JO - Journal of Hypertension
JF - Journal of Hypertension
SN - 0263-6352
IS - 6
ER -