Exercise Therapy in Spinobulbar Muscular Atrophy and Other Neuromuscular Disorders

Julia Rebecka Dahlqvist, John Vissing

19 Citations (Scopus)

Abstract

There is no curative treatment for most neuromuscular disorders. Exercise, as a treatment for these diseases, has therefore received growing attention. When executed properly, exercise can maintain and improve health and reduce the risk of cardiovascular disease, obesity, and diabetes. In persons with muscle wasting due to neuromuscular conditions, however, a common belief has been that physical activity could accelerate degeneration of the diseased muscle and a careful approach to training has therefore been suggested. In this review, we describe the current knowledge about physical training in patients with neuromuscular diseases associated with weakness and wasting. We review studies that have investigated different types of exercise in both myopathies and motor neuron diseases, with particular emphasis on training of persons affected by spinobulbar muscular atrophy (SBMA). Finally, we provide suggestions for future investigations of training in this condition.

Original languageEnglish
JournalJournal of Molecular Neuroscience
Volume58
Issue number3
Pages (from-to)388-393
ISSN0895-8696
DOIs
Publication statusPublished - 2016

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