Abstract
Limbic encephalitis (LE) is frequently associated with malignancy. Non-paraneoplastic LE is less common and in this form, voltage-gated potassium channel (VGKC) antibodies are usually found. However in 2007 the spectrum was further extended by a report on four patients with presumed non-paraneoplastic LE in whom neither VGKC-antibodies nor other antibodies could be found (Samarasekera et al. 2007). Despite immunmodulatory treatment all these patients had severe neurological residual symptoms. Here we describe a further patient in whom extensive diagnostic procedures suggested non-paraneoplastic antibody-negative limbic encephalitis. Although this woman had prolonged status epilepticus during seven weeks, her outcome was excellent.
| Original language | English |
|---|---|
| Journal | Acta neurologica Belgica |
| Volume | 108 |
| Issue number | 1 |
| Pages (from-to) | 21-3 |
| Number of pages | 3 |
| ISSN | 0300-9009 |
| Publication status | Published - Mar 2008 |
| Externally published | Yes |
Keywords
- Adult
- Amnesia/etiology
- Anticonvulsants/therapeutic use
- Autoantibodies/blood
- Autoimmune Diseases of the Nervous System/diagnosis
- Chronic Disease
- Diagnosis, Differential
- Epilepsy, Temporal Lobe/etiology
- Female
- Hippocampus/immunology
- Humans
- Limbic Encephalitis/complications
- Magnetic Resonance Imaging
- Methylprednisolone/therapeutic use
- Personality Disorders/etiology
- Plasmapheresis
- Status Epilepticus/etiology
- Treatment Outcome