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Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis--establishing disease prognosis and monitoring patients

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  1. Calcitonin gene-related peptide - beyond migraine prophylaxis

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  2. Ageing as a risk factor for neurodegenerative disease

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  3. Post-traumatic headache: epidemiology and pathophysiological insights

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  4. Does inflammation have a role in migraine?

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  5. CGRP as the target of new migraine therapies - successful translation from bench to clinic

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  1. Functional-structural assessment of the optic pathways in patients with optic neuritis

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  2. Facing privacy in neuroimaging: removing facial features degrades performance of image analysis methods

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Randomized trial of daily high-dose vitamin D3 in patients with RRMS receiving subcutaneous interferon β-1a

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  4. Author response: Nationwide prevalence and incidence study of neuromyelitis optica spectrum disorder in Denmark

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  5. Treatment escalation leads to fewer relapses compared with switching to another moderately effective therapy

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  • Mike P Wattjes
  • Àlex Rovira
  • David Miller
  • Tarek Yousry
  • Maria P Sormani
  • Maria P de Stefano
  • Mar Tintoré
  • Cristina Auger
  • Carmen Tur
  • Massimo Filippi
  • Maria A Rocca
  • Franz Fazekas
  • Ludwig Kappos
  • Chris Polman
  • Frederik Barkhof
  • Xavier Montalban
  • MAGNIMS study group
  • Jette Lautrup Battistini Frederiksen
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The role of MRI in the assessment of multiple sclerosis (MS) goes far beyond the diagnostic process. MRI techniques can be used as regular monitoring to help stage patients with MS and measure disease progression. MRI can also be used to measure lesion burden, thus providing useful information for the prediction of long-term disability. With the introduction of a new generation of immunomodulatory and/or immunosuppressive drugs for the treatment of MS, MRI also makes an important contribution to the monitoring of treatment, and can be used to determine baseline tissue damage and detect subsequent repair. This use of MRI can help predict treatment response and assess the efficacy and safety of new therapies. In the second part of the MAGNIMS (Magnetic Resonance Imaging in MS) network's guidelines on the use of MRI in MS, we focus on the implementation of this technique in prognostic and monitoring tasks. We present recommendations on how and when to use MRI for disease monitoring, and discuss some promising MRI approaches that may be introduced into clinical practice in the near future.

Original languageEnglish
JournalNature reviews. Neurology
Volume11
Issue number10
Pages (from-to)597-606
Number of pages10
ISSN1759-4758
DOIs
Publication statusPublished - Oct 2015

ID: 46031329