Evaluating Tumor Quantification in Place of Proportions in Prostate Cancer: Principles of the ProQuant Group

Andrew J Vickers; Samson Fine; ProQuant Group

doi:10.1016/j.eururo.2025.11.013

Evaluating Tumor Quantification in Place of Proportions in Prostate Cancer: Principles of the ProQuant Group

Andrew J Vickers^*, Samson Fine, ProQuant Group

^*Corresponding author for this work

Department of Urology

Abstract

We describe the rationale for using quantification of Gleason pattern 4 rather than the proportion of Gleason patterns for risk stratification in prostate cancer, as proposed by the ProQuant Group. We outline research that will be conducted to assess this strategy, and invite individuals interested in collaboration to join the group.

Original language	English
Journal	European Urology
Volume	89
Issue number	4
Pages (from-to)	298-301
Number of pages	4
ISSN	0302-2838
DOIs	https://doi.org/10.1016/j.eururo.2025.11.013
Publication status	Published - 2026

Keywords

Humans
Male
Prostatic Neoplasms/pathology
Neoplasm Grading
Risk Assessment

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10.1016/j.eururo.2025.11.013

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title = "Evaluating Tumor Quantification in Place of Proportions in Prostate Cancer: Principles of the ProQuant Group",

abstract = "We describe the rationale for using quantification of Gleason pattern 4 rather than the proportion of Gleason patterns for risk stratification in prostate cancer, as proposed by the ProQuant Group. We outline research that will be conducted to assess this strategy, and invite individuals interested in collaboration to join the group.",

keywords = "Humans, Male, Prostatic Neoplasms/pathology, Neoplasm Grading, Risk Assessment",

author = "Vickers, \{Andrew J\} and Samson Fine and Andreas R{\o}der and Stroomberg, \{Hein Vincent\} and \{ProQuant Group\}",

year = "2026",

doi = "10.1016/j.eururo.2025.11.013",

language = "English",

volume = "89",

pages = "298--301",

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issn = "0302-2838",

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T2 - Principles of the ProQuant Group

AU - Vickers, Andrew J

AU - Fine, Samson

AU - ProQuant Group

A2 - Røder, Andreas

A2 - Stroomberg, Hein Vincent

PY - 2026

Y1 - 2026

N2 - We describe the rationale for using quantification of Gleason pattern 4 rather than the proportion of Gleason patterns for risk stratification in prostate cancer, as proposed by the ProQuant Group. We outline research that will be conducted to assess this strategy, and invite individuals interested in collaboration to join the group.

AB - We describe the rationale for using quantification of Gleason pattern 4 rather than the proportion of Gleason patterns for risk stratification in prostate cancer, as proposed by the ProQuant Group. We outline research that will be conducted to assess this strategy, and invite individuals interested in collaboration to join the group.

KW - Humans

KW - Male

KW - Prostatic Neoplasms/pathology

KW - Neoplasm Grading

KW - Risk Assessment

U2 - 10.1016/j.eururo.2025.11.013

DO - 10.1016/j.eururo.2025.11.013

M3 - Editorial

C2 - 41419390

SN - 0302-2838

VL - 89

SP - 298

EP - 301

JO - European Urology

JF - European Urology

IS - 4

ER -

Evaluating Tumor Quantification in Place of Proportions in Prostate Cancer: Principles of the ProQuant Group

Abstract

Keywords

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