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The Capital Region of Denmark - a part of Copenhagen University Hospital
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EUS-guided through-the-needle microbiopsy of pancreatic cysts: Technical aspects (with video)

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DOI

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  1. Impact of the COVID-19 pandemic on gastrointestinal endoscopy in Africa

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  2. Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members

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Pancreatic cystic lesions are frequently encountered and diagnostically challenging as some of the cysts may have malignant potential (mucinous) while others are completely benign (serous). EUS-guided through-the-needle biopsy (EUS-TTNB) of the cyst wall has recently been introduced as an alternative to cyst fluid cytology. Several studies have shown that microbiopsies outperform cytology in terms of distinction between mucinous and nonmucinous lesions, but also in determining the specific cyst diagnosis. However, little is known about the technical aspects of tissue sampling with TTNB. Herein, we summarize our experience with the procedure in a tertiary referral center and discuss indications, technical aspects, and safety of the procedure. Most adverse events (AEs) associated with the procedure are mild, but there is emerging evidence that the rate of postprocedural pancreatitis is higher compared to standard fine-needle aspiration. The added diagnostic yield should therefore be placed in perspective with an increased risk of AEs. Prospective studies are warranted to fully identify which patient groups could benefit from EUS-TTNB.

Original languageEnglish
JournalEndoscopic Ultrasound
Volume9
Issue number4
Pages (from-to)220-224
Number of pages5
ISSN2303-9027
DOIs
Publication statusPublished - 1 Jul 2020

    Research areas

  • EUS, intraductal papillary mucinous neoplasm, microbiopsy, pancreatic cyst, pancreatic cystic lesion, through-the-needle biopsy

ID: 60232680