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The Capital Region of Denmark - a part of Copenhagen University Hospital
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EUS-B for suspected left adrenal metastasis in lung cancer

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  1. Assessment of competence in local anaesthetic thoracoscopy: development and validity investigation of a new assessment tool

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Malign pleuraeffusion

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  3. Automatic and Objective Assessment of Motor Skills Performance in Flexible Bronchoscopy

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Background: Several studies have reported the efficacy of esophageal ultrasound-guided fine needle aspiration (EUS-FNA) for the detection of metastases in the left adrenal gland (LAG) in patients with lung cancer. Currently we have only limited evidence based on small studies on the usefulness of EUS-B [endobronchial ultrasound (EBUS) scope into the esophagus] to provide tissue proof of suspected LAG metastases. The objectives of this study are to investigate feasibility, safety and diagnostic yield of EUS-B-FNA in LAG analysis in patients with proven or suspected lung cancer.

Methods: In two Danish hospitals, a systematic search in the electronic database for patients who underwent EUS-B-FNA of the LAG for suspected or proven lung cancer was performed retrospectively between January 1st, 2015 and December 31st, 2017. Computed tomography (CT), positron emission tomography-CT, endoscopy, pathology and follow-up data were acquired.

Results: One hundred and thirty-five patients were included; the prevalence of biopsy proven LAG malignancy was 30% (40/135). A total of 87% (117/135) of EUS-B-FNA samples were adequate (i.e., containing adrenal or malignant cells). No complications were observed.

Conclusions: We present the largest cohort of patients ever reported showing that EUS-B-FNA of the LAG is a safe and feasible procedure and should therefore be used for staging purposes in patients with lung cancer and a suspicious LAG.

Original languageEnglish
JournalJournal of Thoracic Disease
Volume12
Issue number3
Pages (from-to)258-263
Number of pages6
ISSN2072-1439
DOIs
Publication statusPublished - Mar 2020

ID: 61216014