Harvard
Kim, SY, Lohmueller, KE, Albrechtsen, A, Li, Y, Korneliussen, T, Tian, G, Grarup, N, Jiang, T, Andersen, G, Witte, DR
, Jorgensen, T, Hansen, T, Pedersen, O, Wang, J & Nielsen, R 2011, '
Estimation of allele frequency and association mapping using next-generation sequencing data'
B M C Bioinformatics, vol. 12, pp. 231.
https://doi.org/10.1186/1471-2105-12-231APA
Kim, S. Y., Lohmueller, K. E., Albrechtsen, A., Li, Y., Korneliussen, T., Tian, G., ... Nielsen, R. (2011).
Estimation of allele frequency and association mapping using next-generation sequencing data.
B M C Bioinformatics,
12, 231.
https://doi.org/10.1186/1471-2105-12-231CBE
Kim SY, Lohmueller KE, Albrechtsen A, Li Y, Korneliussen T, Tian G, Grarup N, Jiang T, Andersen G, Witte DR
, Jorgensen T, Hansen T, Pedersen O, Wang J, Nielsen R. 2011.
Estimation of allele frequency and association mapping using next-generation sequencing data.
B M C Bioinformatics. 12:231.
https://doi.org/10.1186/1471-2105-12-231MLA
Vancouver
Author
Kim, Su Yeon ; Lohmueller, Kirk E ; Albrechtsen, Anders ; Li, Yingrui ; Korneliussen, Thorfinn ; Tian, Geng ; Grarup, Niels ; Jiang, Tao ; Andersen, Gitte ; Witte, Daniel Rinse
; Jorgensen, Torben ; Hansen, Torben ; Pedersen, Oluf ; Wang, Jun ; Nielsen, Rasmus. /
Estimation of allele frequency and association mapping using next-generation sequencing data. In:
B M C Bioinformatics. 2011 ; Vol. 12. pp. 231.
Bibtex
@article{56475f07e9454438896bfb66c0e7de4b,
title = "Estimation of allele frequency and association mapping using next-generation sequencing data",
abstract = "Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g., <15X). However, SNP calling and allele frequency estimation in such studies is associated with substantial statistical uncertainty because of varying coverage and high error rates.",
keywords = "Gene Frequency, Genetics, Population, Genotype, High-Throughput Nucleotide Sequencing, Humans, Likelihood Functions, Polymorphism, Single Nucleotide, Sequence Analysis, DNA",
author = "Kim, {Su Yeon} and Lohmueller, {Kirk E} and Anders Albrechtsen and Yingrui Li and Thorfinn Korneliussen and Geng Tian and Niels Grarup and Tao Jiang and Gitte Andersen and Witte, {Daniel Rinse} and Torben Jorgensen and Torben Hansen and Oluf Pedersen and Jun Wang and Rasmus Nielsen",
year = "2011",
doi = "10.1186/1471-2105-12-231",
language = "English",
volume = "12",
pages = "231",
journal = "BMC Bioinformatics",
issn = "1471-2105",
publisher = "BioMed Central Ltd",
}
RIS
TY - JOUR
T1 - Estimation of allele frequency and association mapping using next-generation sequencing data
AU - Kim, Su Yeon
AU - Lohmueller, Kirk E
AU - Albrechtsen, Anders
AU - Li, Yingrui
AU - Korneliussen, Thorfinn
AU - Tian, Geng
AU - Grarup, Niels
AU - Jiang, Tao
AU - Andersen, Gitte
AU - Witte, Daniel Rinse
AU - Jorgensen, Torben
AU - Hansen, Torben
AU - Pedersen, Oluf
AU - Wang, Jun
AU - Nielsen, Rasmus
PY - 2011
Y1 - 2011
N2 - Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g., <15X). However, SNP calling and allele frequency estimation in such studies is associated with substantial statistical uncertainty because of varying coverage and high error rates.
AB - Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g., <15X). However, SNP calling and allele frequency estimation in such studies is associated with substantial statistical uncertainty because of varying coverage and high error rates.
KW - Gene Frequency
KW - Genetics, Population
KW - Genotype
KW - High-Throughput Nucleotide Sequencing
KW - Humans
KW - Likelihood Functions
KW - Polymorphism, Single Nucleotide
KW - Sequence Analysis, DNA
U2 - 10.1186/1471-2105-12-231
DO - 10.1186/1471-2105-12-231
M3 - Journal article
VL - 12
SP - 231
JO - BMC Bioinformatics
JF - BMC Bioinformatics
SN - 1471-2105
ER -
