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Estimation of allele frequency and association mapping using next-generation sequencing data

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Harvard

Kim, SY, Lohmueller, KE, Albrechtsen, A, Li, Y, Korneliussen, T, Tian, G, Grarup, N, Jiang, T, Andersen, G, Witte, DR, Jorgensen, T, Hansen, T, Pedersen, O, Wang, J & Nielsen, R 2011, 'Estimation of allele frequency and association mapping using next-generation sequencing data' B M C Bioinformatics, vol. 12, pp. 231. https://doi.org/10.1186/1471-2105-12-231

APA

Kim, S. Y., Lohmueller, K. E., Albrechtsen, A., Li, Y., Korneliussen, T., Tian, G., ... Nielsen, R. (2011). Estimation of allele frequency and association mapping using next-generation sequencing data. B M C Bioinformatics, 12, 231. https://doi.org/10.1186/1471-2105-12-231

CBE

Kim SY, Lohmueller KE, Albrechtsen A, Li Y, Korneliussen T, Tian G, Grarup N, Jiang T, Andersen G, Witte DR, Jorgensen T, Hansen T, Pedersen O, Wang J, Nielsen R. 2011. Estimation of allele frequency and association mapping using next-generation sequencing data. B M C Bioinformatics. 12:231. https://doi.org/10.1186/1471-2105-12-231

MLA

Vancouver

Author

Kim, Su Yeon ; Lohmueller, Kirk E ; Albrechtsen, Anders ; Li, Yingrui ; Korneliussen, Thorfinn ; Tian, Geng ; Grarup, Niels ; Jiang, Tao ; Andersen, Gitte ; Witte, Daniel Rinse ; Jorgensen, Torben ; Hansen, Torben ; Pedersen, Oluf ; Wang, Jun ; Nielsen, Rasmus. / Estimation of allele frequency and association mapping using next-generation sequencing data. In: B M C Bioinformatics. 2011 ; Vol. 12. pp. 231.

Bibtex

@article{56475f07e9454438896bfb66c0e7de4b,
title = "Estimation of allele frequency and association mapping using next-generation sequencing data",
abstract = "Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g., <15X). However, SNP calling and allele frequency estimation in such studies is associated with substantial statistical uncertainty because of varying coverage and high error rates.",
keywords = "Gene Frequency, Genetics, Population, Genotype, High-Throughput Nucleotide Sequencing, Humans, Likelihood Functions, Polymorphism, Single Nucleotide, Sequence Analysis, DNA",
author = "Kim, {Su Yeon} and Lohmueller, {Kirk E} and Anders Albrechtsen and Yingrui Li and Thorfinn Korneliussen and Geng Tian and Niels Grarup and Tao Jiang and Gitte Andersen and Witte, {Daniel Rinse} and Torben Jorgensen and Torben Hansen and Oluf Pedersen and Jun Wang and Rasmus Nielsen",
year = "2011",
doi = "10.1186/1471-2105-12-231",
language = "English",
volume = "12",
pages = "231",
journal = "BMC Bioinformatics",
issn = "1471-2105",
publisher = "BioMed Central Ltd",

}

RIS

TY - JOUR

T1 - Estimation of allele frequency and association mapping using next-generation sequencing data

AU - Kim, Su Yeon

AU - Lohmueller, Kirk E

AU - Albrechtsen, Anders

AU - Li, Yingrui

AU - Korneliussen, Thorfinn

AU - Tian, Geng

AU - Grarup, Niels

AU - Jiang, Tao

AU - Andersen, Gitte

AU - Witte, Daniel Rinse

AU - Jorgensen, Torben

AU - Hansen, Torben

AU - Pedersen, Oluf

AU - Wang, Jun

AU - Nielsen, Rasmus

PY - 2011

Y1 - 2011

N2 - Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g., <15X). However, SNP calling and allele frequency estimation in such studies is associated with substantial statistical uncertainty because of varying coverage and high error rates.

AB - Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g., <15X). However, SNP calling and allele frequency estimation in such studies is associated with substantial statistical uncertainty because of varying coverage and high error rates.

KW - Gene Frequency

KW - Genetics, Population

KW - Genotype

KW - High-Throughput Nucleotide Sequencing

KW - Humans

KW - Likelihood Functions

KW - Polymorphism, Single Nucleotide

KW - Sequence Analysis, DNA

U2 - 10.1186/1471-2105-12-231

DO - 10.1186/1471-2105-12-231

M3 - Journal article

VL - 12

SP - 231

JO - BMC Bioinformatics

JF - BMC Bioinformatics

SN - 1471-2105

ER -

ID: 34686186