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ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults

Research output: Contribution to journalJournal articleResearchpeer-review

  1. An international study of the quality of life of adult patients treated with home parenteral nutrition

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The effect of glucagon-like peptide-1 and glucagon-like peptide-2 on microcirculation: a systematic review

    Research output: Contribution to journalReviewResearchpeer-review

  3. Novel GLP-1/GLP-2 co-agonists display marked effects on gut volume and improves glycemic control in mice

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Loris Pironi
  • Jann Arends
  • Janet Baxter
  • Federico Bozzetti
  • Rosa Burgos Peláez
  • Cristina Cuerda
  • Alastair Forbes
  • Simon Gabe
  • Lyn Gillanders
  • Mette Holst
  • Palle Bekker Jeppesen
  • Francisca Joly
  • Darlene Kelly
  • Stanislaw Klek
  • Øivind Irtun
  • Sw Olde Damink
  • Marina Panisic
  • Henrik Højgaard Rasmussen
  • Michael Staun
  • Kinga Szczepanek
  • André Van Gossum
  • Geert Wanten
  • Stéphane Michel Schneider
  • Jon Shaffer
  • the Home Artificial Nutrition & Chronic Intestinal Failure and the Acute Intestinal Failure Special Interest Groups of ESPEN
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BACKGROUND & AIMS: Intestinal failure (IF) is not included in the list of PubMed Mesh terms, as failure is the term describing a state of non functioning of other organs, and as such is not well recognized. No scientific society has yet devised a formal definition and classification of IF. The European Society for Clinical Nutrition and Metabolism guideline committee endorsed its "home artificial nutrition and chronic IF" and "acute IF" special interest groups to write recommendations on these issues.

METHODS: After a Medline Search, in December 2013, for "intestinal failure" and "review"[Publication Type], the project was developed using the Delphi round methodology. The final consensus was reached on March 2014, after 5 Delphi rounds and two live meetings.

RESULTS: The recommendations comprise the definition of IF, a functional and a pathophysiological classification for both acute and chronic IF and a clinical classification of chronic IF. IF was defined as "the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth".

CONCLUSIONS: This formal definition and classification of IF, will facilitate communication and cooperation among professionals in clinical practice, organization and management, and research.

Original languageEnglish
JournalClinical nutrition (Edinburgh, Scotland)
Issue number2
Pages (from-to)171-80
Publication statusPublished - 2015

ID: 45056705