Enterococcus faecalis infective endocarditis: a pilot study of the relationship between duration of gentamicin treatment and outcome

Anders Dahl, Rasmus V Rasmussen, Henning Bundgaard, Christian Hassager, Louise E Bruun, Trine K Lauridsen, Claus Moser, Peter Sogaard, Magnus Arpi, Niels Eske Bruun

91 Citations (Scopus)

Abstract

Because of the nephrotoxic effects of aminoglycosides, the Danish guidelines on infective endocarditis were changed in January 2007, reducing gentamicin treatment in enterococcal infective endocarditis from 4 to 6 weeks to only 2 weeks. In this pilot study, we compare outcomes in patients with Enterococcus faecalis infective endocarditis treated in the years before and after endorsement of these new recommendations.
Original languageEnglish
JournalCirculation (Baltimore)
Volume127
Issue number17
Pages (from-to)1810-7
Number of pages8
ISSN0009-7322
DOIs
Publication statusPublished - 30 Apr 2013

Keywords

  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents
  • Cohort Studies
  • Denmark
  • Endocarditis, Bacterial
  • Enterococcus faecalis
  • Female
  • Follow-Up Studies
  • Gentamicins
  • Gram-Positive Bacterial Infections
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Prospective Studies
  • Registries
  • Retrospective Studies
  • Treatment Outcome

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