Endurance training: an effective and safe treatment for patients with LGMD2I

M-L Sveen; T D Jeppesen; S Hauerslev; T O Krag; J Vissing

doi:10.1212/01.wnl.0000250358.32199.24

Endurance training: an effective and safe treatment for patients with LGMD2I

M-L Sveen, T D Jeppesen, S Hauerslev, T O Krag, J Vissing

Department of Neurology

Abstract

We studied the effect of aerobic training on conditioning in patients with limb-girdle muscular dystrophy type 2I (LGMD2I). Nine patients with LGMD2I cycled fifty 30-minute sessions at 65% of their maximal oxygen uptake over 12 weeks. Training significantly improved work capacity, paralleled by self-reported improvements. Creatine kinase levels did not increase significantly, and muscle morphology was unaffected. Moderate-intensity endurance training is a safe method to increase exercise performance and daily function in patients with LGMD2I.

Original language	English
Journal	Neurology
Volume	68
Issue number	1
Pages (from-to)	59-61
Number of pages	3
ISSN	0028-3878
DOIs	https://doi.org/10.1212/01.wnl.0000250358.32199.24
Publication status	Published - 2 Jan 2007

Keywords

Adult
Exercise/physiology
Exercise Therapy/methods
Female
Humans
Male
Middle Aged
Muscle, Skeletal/pathology
Muscular Dystrophies, Limb-Girdle/pathology
Physical Endurance/physiology

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10.1212/01.wnl.0000250358.32199.24

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title = "Endurance training: an effective and safe treatment for patients with LGMD2I",

abstract = "We studied the effect of aerobic training on conditioning in patients with limb-girdle muscular dystrophy type 2I (LGMD2I). Nine patients with LGMD2I cycled fifty 30-minute sessions at 65% of their maximal oxygen uptake over 12 weeks. Training significantly improved work capacity, paralleled by self-reported improvements. Creatine kinase levels did not increase significantly, and muscle morphology was unaffected. Moderate-intensity endurance training is a safe method to increase exercise performance and daily function in patients with LGMD2I.",

keywords = "Adult, Exercise/physiology, Exercise Therapy/methods, Female, Humans, Male, Middle Aged, Muscle, Skeletal/pathology, Muscular Dystrophies, Limb-Girdle/pathology, Physical Endurance/physiology",

author = "M-L Sveen and Jeppesen, {T D} and S Hauerslev and Krag, {T O} and J Vissing",

year = "2007",

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language = "English",

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T2 - an effective and safe treatment for patients with LGMD2I

AU - Sveen, M-L

AU - Jeppesen, T D

AU - Hauerslev, S

AU - Krag, T O

AU - Vissing, J

PY - 2007/1/2

Y1 - 2007/1/2

N2 - We studied the effect of aerobic training on conditioning in patients with limb-girdle muscular dystrophy type 2I (LGMD2I). Nine patients with LGMD2I cycled fifty 30-minute sessions at 65% of their maximal oxygen uptake over 12 weeks. Training significantly improved work capacity, paralleled by self-reported improvements. Creatine kinase levels did not increase significantly, and muscle morphology was unaffected. Moderate-intensity endurance training is a safe method to increase exercise performance and daily function in patients with LGMD2I.

AB - We studied the effect of aerobic training on conditioning in patients with limb-girdle muscular dystrophy type 2I (LGMD2I). Nine patients with LGMD2I cycled fifty 30-minute sessions at 65% of their maximal oxygen uptake over 12 weeks. Training significantly improved work capacity, paralleled by self-reported improvements. Creatine kinase levels did not increase significantly, and muscle morphology was unaffected. Moderate-intensity endurance training is a safe method to increase exercise performance and daily function in patients with LGMD2I.

KW - Adult

KW - Exercise/physiology

KW - Exercise Therapy/methods

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Muscle, Skeletal/pathology

KW - Muscular Dystrophies, Limb-Girdle/pathology

KW - Physical Endurance/physiology

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DO - 10.1212/01.wnl.0000250358.32199.24

M3 - Journal article

C2 - 17200494

SN - 0028-3878

VL - 68

SP - 59

EP - 61

JO - Neurology

JF - Neurology

IS - 1

ER -

Endurance training: an effective and safe treatment for patients with LGMD2I

Abstract

Keywords

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