Endoscopic treatment options in peptic ulcer bleeding

Frederik Elbke Hansen; Magnus Ploug; Gitte Maria Jørgensen; John Gásdal Karstensen; Ove B.Schaffalitzky de Muckadell; Stig Borbjerg Laursen

doi:10.61409/V04240254

Endoscopic treatment options in peptic ulcer bleeding

Translated title of the contribution: Not Available

Frederik Elbke Hansen, Magnus Ploug, Gitte Maria Jørgensen, John Gásdal Karstensen, Ove B.Schaffalitzky de Muckadell, Stig Borbjerg Laursen

Gastrounit, Surgical Division

Abstract

This review evaluates the evidence for the use of over-the-scope clips (OTSC), topical haemostatic agents (THA), and prophylactic embolisation (PE) in patients with peptic ulcer bleeding (PUB). The use of OTSC and THA may have the potential to increase the rate of endoscopic haemostasis in PUB not responding to conventional endoscopic treatment. In patients at high risk of recurrent bleeding, the performance of PE after achieving endoscopic haemostasis can reduce the risk of rebleeding and the need for surgery. Implementation of a local treatment protocol including these modalities may improve patient outcomes.

Translated title of the contribution	Not Available
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	186
Issue number	35
ISSN	0041-5782
DOIs	https://doi.org/10.61409/V04240254
Publication status	Published - 26 Aug 2024

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10.61409/V04240254

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title = "Endoscopic treatment options in peptic ulcer bleeding",

abstract = "This review evaluates the evidence for the use of over-the-scope clips (OTSC), topical haemostatic agents (THA), and prophylactic embolisation (PE) in patients with peptic ulcer bleeding (PUB). The use of OTSC and THA may have the potential to increase the rate of endoscopic haemostasis in PUB not responding to conventional endoscopic treatment. In patients at high risk of recurrent bleeding, the performance of PE after achieving endoscopic haemostasis can reduce the risk of rebleeding and the need for surgery. Implementation of a local treatment protocol including these modalities may improve patient outcomes.",

keywords = "Humans, Peptic Ulcer Hemorrhage/therapy, Hemostasis, Endoscopic/methods, Embolization, Therapeutic/methods, Hemostatics/therapeutic use, Surgical Instruments",

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AU - Hansen, Frederik Elbke

AU - Ploug, Magnus

AU - Jørgensen, Gitte Maria

AU - Karstensen, John Gásdal

AU - de Muckadell, Ove B.Schaffalitzky

AU - Laursen, Stig Borbjerg

N1 - Publisher Copyright: Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

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Y1 - 2024/8/26

N2 - This review evaluates the evidence for the use of over-the-scope clips (OTSC), topical haemostatic agents (THA), and prophylactic embolisation (PE) in patients with peptic ulcer bleeding (PUB). The use of OTSC and THA may have the potential to increase the rate of endoscopic haemostasis in PUB not responding to conventional endoscopic treatment. In patients at high risk of recurrent bleeding, the performance of PE after achieving endoscopic haemostasis can reduce the risk of rebleeding and the need for surgery. Implementation of a local treatment protocol including these modalities may improve patient outcomes.

AB - This review evaluates the evidence for the use of over-the-scope clips (OTSC), topical haemostatic agents (THA), and prophylactic embolisation (PE) in patients with peptic ulcer bleeding (PUB). The use of OTSC and THA may have the potential to increase the rate of endoscopic haemostasis in PUB not responding to conventional endoscopic treatment. In patients at high risk of recurrent bleeding, the performance of PE after achieving endoscopic haemostasis can reduce the risk of rebleeding and the need for surgery. Implementation of a local treatment protocol including these modalities may improve patient outcomes.

KW - Humans

KW - Peptic Ulcer Hemorrhage/therapy

KW - Hemostasis, Endoscopic/methods

KW - Embolization, Therapeutic/methods

KW - Hemostatics/therapeutic use

KW - Surgical Instruments

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DO - 10.61409/V04240254

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SN - 0041-5782

VL - 186

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 35

ER -

Endoscopic treatment options in peptic ulcer bleeding

Abstract

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