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Endocrine, metabolic and cardiovascular responses to adrenaline after abdominal surgery

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  1. Urinary growth hormone excretion in acromegaly: diagnostic value in mild disease activity

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  2. Impaired pancreatic polypeptide response to a meal in type 1 diabetic patients: vagal neuropathy or islet cell dysfunction?

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  3. Bone metabolism in obesity: changes related to severe overweight and dietary weight reduction.

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  4. Effects of thyrotropin-releasing hormone on regional cerebral blood flow in man

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  1. Preoperative high-dose Steroids in Total Knee and Hip Arthroplasty - Protocols for three randomized controlled trials

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  2. Perioperative care guidelines: conflicts and controversies

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Adrenaline-induced changes in heart rate, blood pressure, plasma adrenaline and noradrenaline, cortisol, glucagon, insulin, cAMP, glucose lactate, glycerol and beta-hydroxybutyrate were studied preoperatively and 4 and 24 h after skin incision in 8 patients undergoing elective cholecystectomy. Late postoperative responses of blood glucose, plasma cAMP, lactate and glycerol to adrenaline infusion were reduced, whereas other responses were unaffected. Blood glucose appearance and disappearance rate as assessed by [3H]3-glucose infusion was unchanged pre- and postoperatively. The increase in glucose appearance rate following adrenaline was similar pre- and postoperatively. These findings suggest that several beta-receptor-mediated responses to adrenaline are reduced after abdominal surgery.
Original languageEnglish
JournalActa Endocrinologica (Copenh)
Volume123
Issue number2
Pages (from-to)143-8
Number of pages6
ISSN0001-5598
Publication statusPublished - Aug 1990

    Research areas

  • Adult, Blood Glucose, Blood Pressure, Catecholamines, Cholecystectomy, Cyclic AMP, Dermatologic Surgical Procedures, Epinephrine, Female, Glucagon, Glycerol, Heart Rate, Humans, Hydrocortisone, Hydroxybutyrates, Infusions, Intravenous, Insulin, Lactates, Postoperative Period

ID: 40238088