Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic

D M L Saunte; M Pereiro-Ferreirós; C Rodríguez-Cerdeira; A Y Sergeev; M Arabatzis; A Prohić; B M Piraccini; P Lecerf; P Nenoff; L P Kotrekhova; P P Bosshard; V Padovese; J C Szepietowski; B Sigurgeirsson; R J Nowicki; P Schmid-Grendelmeier; R J Hay

doi:10.1111/jdv.17241

Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic

D M L Saunte, M Pereiro-Ferreirós, C Rodríguez-Cerdeira, A Y Sergeev, M Arabatzis, A Prohić, B M Piraccini, P Lecerf, P Nenoff, L P Kotrekhova, P P Bosshard, V Padovese, J C Szepietowski, B Sigurgeirsson, R J Nowicki, P Schmid-Grendelmeier, R J Hay

99 Citations (Scopus)

Abstract

BACKGROUND: Dermatophytosis is a world-wide distributed common infection. Antifungal drug resistance in dermatophytosis used to be rare, but unfortunately the current Indian epidemic of atypical widespread recalcitrant and terbinafine-resistant dermatophytosis is spreading and has sporadically been reported in Europe.

OBJECTIVES: To explore the occurrence of clinical and mycological proven antifungal drug resistance in dermatophytes in Europe.

METHODS: A standardized questionnaire was distributed through the EADV Task Force of Mycology network to dermatologists in Europe.

RESULTS: Representatives from 20 countries completed the questionnaires of which 17 (85 %) had observed clinical and/or mycological confirmed antifungal resistance, two countries published cases of antifungal resistance and one country had no known cases.

CONCLUSIONS: This pilot study confirms that both clinical and mycological antifungal resistance exist in Europe.

Original language	English
Journal	Journal of the European Academy of Dermatology and Venereology : JEADV
Volume	35
Issue number	7
Pages (from-to)	1582-1586
Number of pages	5
ISSN	0926-9959
DOIs	https://doi.org/10.1111/jdv.17241
Publication status	Published - Jul 2021
Externally published	Yes

Keywords

Antifungal Agents/therapeutic use
Europe
Humans
Pilot Projects
Tinea/drug therapy
Treatment Failure

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10.1111/jdv.17241

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Saunte, D. M. L., Pereiro-Ferreirós, M., Rodríguez-Cerdeira, C., Sergeev, A. Y., Arabatzis, M., Prohić, A., Piraccini, B. M., Lecerf, P., Nenoff, P., Kotrekhova, L. P., Bosshard, P. P., Padovese, V., Szepietowski, J. C., Sigurgeirsson, B., Nowicki, R. J., Schmid-Grendelmeier, P., & Hay, R. J. (2021). Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic. Journal of the European Academy of Dermatology and Venereology : JEADV, 35(7), 1582-1586. https://doi.org/10.1111/jdv.17241

Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic. / Saunte, D M L; Pereiro-Ferreirós, M; Rodríguez-Cerdeira, C et al.
In: Journal of the European Academy of Dermatology and Venereology : JEADV, Vol. 35, No. 7, 07.2021, p. 1582-1586.

Research output: Contribution to journal › Journal article › Research › peer-review

Saunte, DML, Pereiro-Ferreirós, M, Rodríguez-Cerdeira, C, Sergeev, AY, Arabatzis, M, Prohić, A, Piraccini, BM, Lecerf, P, Nenoff, P, Kotrekhova, LP, Bosshard, PP, Padovese, V, Szepietowski, JC, Sigurgeirsson, B, Nowicki, RJ, Schmid-Grendelmeier, P & Hay, RJ 2021, 'Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic', Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 35, no. 7, pp. 1582-1586. https://doi.org/10.1111/jdv.17241

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abstract = "BACKGROUND: Dermatophytosis is a world-wide distributed common infection. Antifungal drug resistance in dermatophytosis used to be rare, but unfortunately the current Indian epidemic of atypical widespread recalcitrant and terbinafine-resistant dermatophytosis is spreading and has sporadically been reported in Europe.OBJECTIVES: To explore the occurrence of clinical and mycological proven antifungal drug resistance in dermatophytes in Europe.METHODS: A standardized questionnaire was distributed through the EADV Task Force of Mycology network to dermatologists in Europe.RESULTS: Representatives from 20 countries completed the questionnaires of which 17 (85 \%) had observed clinical and/or mycological confirmed antifungal resistance, two countries published cases of antifungal resistance and one country had no known cases.CONCLUSIONS: This pilot study confirms that both clinical and mycological antifungal resistance exist in Europe.",

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doi = "10.1111/jdv.17241",

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T1 - Emerging antifungal treatment failure of dermatophytosis in Europe

T2 - take care or it may become endemic

AU - Saunte, D M L

AU - Pereiro-Ferreirós, M

AU - Rodríguez-Cerdeira, C

AU - Sergeev, A Y

AU - Arabatzis, M

AU - Prohić, A

AU - Piraccini, B M

AU - Lecerf, P

AU - Nenoff, P

AU - Kotrekhova, L P

AU - Bosshard, P P

AU - Padovese, V

AU - Szepietowski, J C

AU - Sigurgeirsson, B

AU - Nowicki, R J

AU - Schmid-Grendelmeier, P

AU - Hay, R J

PY - 2021/7

Y1 - 2021/7

N2 - BACKGROUND: Dermatophytosis is a world-wide distributed common infection. Antifungal drug resistance in dermatophytosis used to be rare, but unfortunately the current Indian epidemic of atypical widespread recalcitrant and terbinafine-resistant dermatophytosis is spreading and has sporadically been reported in Europe.OBJECTIVES: To explore the occurrence of clinical and mycological proven antifungal drug resistance in dermatophytes in Europe.METHODS: A standardized questionnaire was distributed through the EADV Task Force of Mycology network to dermatologists in Europe.RESULTS: Representatives from 20 countries completed the questionnaires of which 17 (85 %) had observed clinical and/or mycological confirmed antifungal resistance, two countries published cases of antifungal resistance and one country had no known cases.CONCLUSIONS: This pilot study confirms that both clinical and mycological antifungal resistance exist in Europe.

AB - BACKGROUND: Dermatophytosis is a world-wide distributed common infection. Antifungal drug resistance in dermatophytosis used to be rare, but unfortunately the current Indian epidemic of atypical widespread recalcitrant and terbinafine-resistant dermatophytosis is spreading and has sporadically been reported in Europe.OBJECTIVES: To explore the occurrence of clinical and mycological proven antifungal drug resistance in dermatophytes in Europe.METHODS: A standardized questionnaire was distributed through the EADV Task Force of Mycology network to dermatologists in Europe.RESULTS: Representatives from 20 countries completed the questionnaires of which 17 (85 %) had observed clinical and/or mycological confirmed antifungal resistance, two countries published cases of antifungal resistance and one country had no known cases.CONCLUSIONS: This pilot study confirms that both clinical and mycological antifungal resistance exist in Europe.

KW - Antifungal Agents/therapeutic use

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KW - Humans

KW - Pilot Projects

KW - Tinea/drug therapy

KW - Treatment Failure

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SN - 0926-9959

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JO - Journal of the European Academy of Dermatology and Venereology : JEADV

JF - Journal of the European Academy of Dermatology and Venereology : JEADV

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Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic

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Keywords

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