Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Electroconvulsive therapy and later stroke in patients with affective disorders

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Evidence for oestrogen sensitivity in perinatal depression: pharmacological sex hormone manipulation study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Suicidal behaviour among persons with attention-deficit hyperactivity disorder

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Attention-deficit hyperactivity disorder and anxiety disorders as precursors of bipolar disorder onset in adulthood

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Detail, dynamics and depth: useful correctives for some current research trends

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Possible Modifiers of the Association Between Change in Weight Status From Child Through Adult Ages and Later Risk of Type 2 Diabetes

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The effect of erythropoietin on electroconvulsive stimulation induced cognitive impairment in rats

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Electroconvulsive therapy, depression severity and mortality: Data from the Danish National Patient Registry

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

The long-term effects of electroconvulsive therapy (ECT) on the risk of stroke are unknown. We examined the association between ECT and risk of incident or recurrent stroke. A cohort of 174 534 patients diagnosed with affective disorder between 2005 and 2016 in the Danish National Patient Registry were followed for stroke until November 2016. The association between ECT and stroke was analysed using Cox regression with multiple adjustment and propensity-score matching on sociodemographic and clinical variables. In 162 595 patients without previous stroke, 5781 (3.6%) were treated with ECT. The total number of patients developing stroke during follow-up was 3665, of whom 165 had been treated with ECT. In patients <50 years, ECT was not associated with stroke (adjusted hazard ratio (HR) = 1.29, 95% CI 0.87-1.93). In patients ≥50, ECT was associated with a lower risk of stroke (adjusted HR = 0.69, 95% CI 0.57-0.89), but this estimate was likely influenced by competing mortality risk. Of 11 939 patients with a history of stroke, 228 (1.9%) were treated with ECT. During follow-up, 2330 (19.5%) patients had a recurrence, of which 26 were patients treated with ECT. ECT was not associated with risk of a new event (HR = 0.69, 95% CI 0.46-1.00; P = 0.05). ECT is not associated with an elevated risk of incident or recurrent stroke.Declaration of interestNone.

Original languageEnglish
JournalThe British journal of psychiatry : the journal of mental science
Volume214
Issue number3
Pages (from-to)168-170
Number of pages3
ISSN0007-1250
DOIs
Publication statusPublished - 1 Mar 2019

    Research areas

  • Electroconvulsive therapy, clinical neurology, epidemiology

ID: 55199433