Electrochemotherapy for large cutaneous recurrence of breast cancer: a phase II clinical trial

Louise Wichmann Matthiessen; Helle Hjorth Johannesen; Helle Westergren Hendel; Timothy Moss; Claus Kamby; Julie Gehl

doi:10.3109/0284186X.2012.685524

Electrochemotherapy for large cutaneous recurrence of breast cancer: a phase II clinical trial

Louise Wichmann Matthiessen, Helle Hjorth Johannesen, Helle Westergren Hendel, Timothy Moss, Claus Kamby, Julie Gehl

Department of Oncology

121 Citations (Scopus)

Abstract

Cutaneous recurrences of breast cancer may cause considerable discomfort due to ulceration, oozing, and pain and can also be difficult to treat. Electrochemotherapy is a localised anticancer treatment using electric pulses to make cell membranes permeable, augmenting uptake of chemotherapeutic drugs, and thus enabling highly efficient tumour cell kill. This is the first systematic investigation of electrochemotherapy for larger cutaneous recurrences of breast cancer.

Original language	English
Journal	Acta Oncologica
Volume	51
Issue number	6
Pages (from-to)	713-21
Number of pages	9
ISSN	0284-186X
DOIs	https://doi.org/10.3109/0284186X.2012.685524
Publication status	Published - 2012

Keywords

Adult
Aged
Antineoplastic Combined Chemotherapy Protocols
Breast Neoplasms
Electrochemotherapy
Female
Follow-Up Studies
Humans
Middle Aged
Neoplasm Recurrence, Local
Neoplasm Staging
Skin Neoplasms
Treatment Outcome

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10.3109/0284186X.2012.685524

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title = "Electrochemotherapy for large cutaneous recurrence of breast cancer: a phase II clinical trial",

abstract = "Cutaneous recurrences of breast cancer may cause considerable discomfort due to ulceration, oozing, and pain and can also be difficult to treat. Electrochemotherapy is a localised anticancer treatment using electric pulses to make cell membranes permeable, augmenting uptake of chemotherapeutic drugs, and thus enabling highly efficient tumour cell kill. This is the first systematic investigation of electrochemotherapy for larger cutaneous recurrences of breast cancer.",

keywords = "Adult, Aged, Antineoplastic Combined Chemotherapy Protocols, Breast Neoplasms, Electrochemotherapy, Female, Follow-Up Studies, Humans, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Staging, Skin Neoplasms, Treatment Outcome",

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language = "English",

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TY - JOUR

T1 - Electrochemotherapy for large cutaneous recurrence of breast cancer

T2 - a phase II clinical trial

AU - Matthiessen, Louise Wichmann

AU - Johannesen, Helle Hjorth

AU - Hendel, Helle Westergren

AU - Moss, Timothy

AU - Kamby, Claus

AU - Gehl, Julie

PY - 2012

Y1 - 2012

N2 - Cutaneous recurrences of breast cancer may cause considerable discomfort due to ulceration, oozing, and pain and can also be difficult to treat. Electrochemotherapy is a localised anticancer treatment using electric pulses to make cell membranes permeable, augmenting uptake of chemotherapeutic drugs, and thus enabling highly efficient tumour cell kill. This is the first systematic investigation of electrochemotherapy for larger cutaneous recurrences of breast cancer.

AB - Cutaneous recurrences of breast cancer may cause considerable discomfort due to ulceration, oozing, and pain and can also be difficult to treat. Electrochemotherapy is a localised anticancer treatment using electric pulses to make cell membranes permeable, augmenting uptake of chemotherapeutic drugs, and thus enabling highly efficient tumour cell kill. This is the first systematic investigation of electrochemotherapy for larger cutaneous recurrences of breast cancer.

KW - Adult

KW - Aged

KW - Antineoplastic Combined Chemotherapy Protocols

KW - Breast Neoplasms

KW - Electrochemotherapy

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Middle Aged

KW - Neoplasm Recurrence, Local

KW - Neoplasm Staging

KW - Skin Neoplasms

KW - Treatment Outcome

UR - https://www.scopus.com/pages/publications/84863860429

U2 - 10.3109/0284186X.2012.685524

DO - 10.3109/0284186X.2012.685524

M3 - Journal article

C2 - 22731832

SN - 0284-186X

VL - 51

SP - 713

EP - 721

JO - Acta Oncologica

JF - Acta Oncologica

IS - 6

ER -

Electrochemotherapy for large cutaneous recurrence of breast cancer: a phase II clinical trial

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Keywords

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