Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity

Pär I Johansson; Anne Marie Sørensen; Anders Perner; Karen-Lise Welling; Michael Wanscher; Claus F Larsen; Sisse R Ostrowski

doi:10.1097/CCM.0b013e31823e9d15

Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity

Pär I Johansson, Anne Marie Sørensen, Anders Perner, Karen-Lise Welling, Michael Wanscher, Claus F Larsen, Sisse R Ostrowski

20 Citations (Scopus)

Abstract

: High patient age is a strong predictor of poor outcome in trauma patients. The present study investigated the effect of age on mortality and biomarkers of sympathoadrenal activation, tissue, endothelial, and glycocalyx damage, coagulation activation/inhibition, fibrinolysis, and inflammation in trauma patients at admission.

Original language	English
Journal	Critical Care Medicine
Volume	40
Issue number	6
Pages (from-to)	1844-50
Number of pages	7
ISSN	0090-3493
DOIs	https://doi.org/10.1097/CCM.0b013e31823e9d15
Publication status	Published - 2012

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Johansson, P. I., Sørensen, A. M., Perner, A., Welling, K-L., Wanscher, M., Larsen, C. F., & Ostrowski, S. R. (2012). Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity. Critical Care Medicine, 40(6), 1844-50. https://doi.org/10.1097/CCM.0b013e31823e9d15

Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity. / Johansson, Pär I; Sørensen, Anne Marie; Perner, Anders et al.

In: Critical Care Medicine, Vol. 40, No. 6, 2012, p. 1844-50.

Research output: Contribution to journal › Journal article › Research › peer-review

Johansson, PI, Sørensen, AM, Perner, A , Welling, K-L , Wanscher, M, Larsen, CF & Ostrowski, SR 2012, 'Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity', Critical Care Medicine, vol. 40, no. 6, pp. 1844-50. https://doi.org/10.1097/CCM.0b013e31823e9d15

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abstract = ": High patient age is a strong predictor of poor outcome in trauma patients. The present study investigated the effect of age on mortality and biomarkers of sympathoadrenal activation, tissue, endothelial, and glycocalyx damage, coagulation activation/inhibition, fibrinolysis, and inflammation in trauma patients at admission.",

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AU - Larsen, Claus F

AU - Ostrowski, Sisse R

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Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity

Abstract

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