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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Effects of a Multidisciplinary Residential Nutritional Rehabilitation Program in Head and Neck Cancer Survivors-Results from the NUTRI-HAB Randomized Controlled Trial

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  1. Beneficial Effect of Mildly Pasteurized Whey Protein on Intestinal Integrity and Innate Defense in Preterm and Near-Term Piglets

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  2. Effect of the natural sweetener xylitol on gut hormone secretion and gastric emptying in humans: a pilot dose-ranging study

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  3. Timing and Frequency of Daily Energy Intake in Adults with Prediabetes and Overweight or Obesity and Their Associations with Body Fat

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  4. Mildly Pasteurized Whey Protein Promotes Gut Tolerance in Immature Piglets Compared with Extensively Heated Whey Protein

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  1. Health-Related Quality of Life Following Total Laryngectomy: A Systematic Review

    Research output: Contribution to journalReviewpeer-review

  2. Impact of time to treatment initiation for patients with oral cavity squamous cell carcinoma: a population-based, retrospective study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. European white paper: oropharyngeal dysphagia in head and neck cancer

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  4. The impact of comorbidities on survival in oral cancer patients: a population-based, case-control study

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  5. Long-term quality of life & functional outcomes after treatment of oropharyngeal cancer

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Head and neck cancer survivors frequently experience nutritional challenges, and proper rehabilitation should be offered. The trial objective was to test the effect of a multidisciplinary residential nutritional rehabilitation programme addressing physical, psychological, and social aspects of eating problems after treatment. In a randomized controlled trial, 71 head and neck cancer survivors recruited through a nationwide survey were randomized to the program or a wait-list control group. Inclusion was based on self-reported interest in participation. The primary outcome was change in body weight. Secondary outcomes included physical function, quality of life, and symptoms of anxiety and depression. Differences between groups at the 3-month follow-up were tested. No significant differences were seen in body weight change, but there were overall trends towards greater improvements in physical function (hand grip strength: p = 0.042; maximal mouth opening: p = 0.072) and quality of life ("Role functioning": p = 0.041; "Speech problems": p = 0.040; "Pain": p = 0.048) in the intervention group. To conclude, a multidisciplinary residential nutritional rehabilitation program had no effect on body weight in head and neck cancer survivors with self-reported interest in participation, but it may have effect on physical function and quality of life. Further research on relevant outcomes, inclusion criteria, and the program's effect in different subgroups is needed.

Original languageEnglish
JournalNutrients
Volume12
Issue number7
ISSN2072-6643
DOIs
Publication statusPublished - 17 Jul 2020

ID: 61228150