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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Effects of a ketogenic diet on brain metabolism in epilepsy

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For a subpopulation of drug-resistant epilepsies, a ketogenic diet constitutes the treatment of choice. A ketogenic diet is a high-fat, low-protein, and low-carbohydrate diet, which induces ketosis. Despite the use in treatment of epilepsy since 1924, the clinical efficacy was not demonstrated in a controlled, randomized trial until 2008, showing its capability of reducing seizure frequency with more than 50%. However, the exact mechanism of this form of treatment is still unknown. We report here a patient with drug-resistant epilepsy on a ketogenic diet, where a brain 18F-FDG PET examination demonstrated a severely decreased uptake in the cerebral cortex bilaterally.
Original languageEnglish
JournalClinical Nuclear Medicine
Volume38
Issue number1
Pages (from-to)38-9
Number of pages2
ISSN0363-9762
DOIs
Publication statusPublished - Jan 2013

    Research areas

  • Brain, Child, Electroencephalography, Epilepsy, Female, Fluorodeoxyglucose F18, Humans, Ketogenic Diet, Multimodal Imaging, Positron-Emission Tomography, Tomography, X-Ray Computed

ID: 43158972