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Effects of 12 weeks' treatment with a proton pump inhibitor on insulin secretion, glucose metabolism and markers of cardiovascular risk in patients with type 2 diabetes: a randomised double-blind prospective placebo-controlled study

K D Hove, Charlotte Brøns, Kai Erik Vinther Færch, S S Lund, J S Petersen, A E Karlsen, Pia Rossing, J F Rehfeld, A Vaag

40 Citations (Scopus)

Abstract

Recent studies suggest that proton pump inhibitor treatment may increase insulin secretion and improve glucose metabolism in type 2 diabetes. In a randomised double-blind prospective placebo-controlled 2 × 2 factorial study, we examined the effect of esomeprazole on insulin secretion, HbA(1c) and cardiovascular risk factors in type 2 diabetes.
Original languageEnglish
JournalDiabetologia
Volume56
Issue number1
Pages (from-to)22-30
Number of pages9
ISSN0012-186X
DOIs
Publication statusPublished - 2013

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