TY - JOUR
T1 - Effective interventions in preventing gestational diabetes mellitus
T2 - A systematic review and meta-analysis
AU - Takele, Wubet Worku
AU - Vesco, Kimberly K.
AU - Josefson, Jami
AU - Redman, Leanne M.
AU - Hannah, Wesley
AU - Bonham, Maxine P.
AU - Chen, Mingling
AU - Chivers, Sian C.
AU - Fawcett, Andrea J.
AU - Grieger, Jessica A.
AU - Habibi, Nahal
AU - Leung, Gloria K.W.
AU - Liu, Kai
AU - Mekonnen, Eskedar G.
AU - Pathirana, Maleesa
AU - Quinteros, Alejandra
AU - Taylor, Rachael
AU - Ukke, Gebresilasea G.
AU - Zhou, Shao J.
AU - Franks, Paul W.
AU - Rich, Stephen S.
AU - Wagner, Robert
AU - Udler, Miriam S.
AU - Tuomi, Tiinamaija
AU - Sweeting, Arianne
AU - Sims, Emily K.
AU - Sherr, Jennifer L.
AU - Semple, Robert K.
AU - Reynolds, Rebecca M.
AU - Redondo, Maria J.
AU - Pratley, Richard E.
AU - Pop-Busui, Rodica
AU - Pollin, Toni I.
AU - Perng, Wei
AU - Pearson, Ewan R.
AU - Ozanne, Susan E.
AU - Owen, Katharine R.
AU - Oram, Richard
AU - Murphy, Rinki
AU - Mohan, Viswanathan
AU - Misra, Shivani
AU - Meigs, James B.
AU - Mathioudakis, Nestoras
AU - ADA/EASD PMDI
A2 - Vilsbøll, Tina
A2 - Nolan, John J.
A2 - Ried-Larsen, Mathias
A2 - Hansen, Torben
A2 - Clemmensen, Christoffer
A2 - Andersen, Mette K.
A2 - Thuesen, Anne Cathrine B.
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/4/20
Y1 - 2024/4/20
N2 - Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the implementation of GDM prevention interventions. Methods: Ovid, MEDLINE/PubMed, and EMBASE databases were searched. The Template for Intervention Description and Replication (TIDieR) framework was used to examine intervention characteristics (who, what, when, where, and how). Subgroup analysis was performed by intervention characteristics. Results: 116 studies involving 40,940 participants are included. Group-based physical activity interventions (RR 0.66; 95% CI 0.46, 0.95) reduce the incidence of GDM compared with individual or mixed (individual and group) delivery format (subgroup p-value = 0.04). Physical activity interventions delivered at healthcare facilities reduce the risk of GDM (RR 0.59; 95% CI 0.49, 0.72) compared with home-based interventions (subgroup p-value = 0.03). No other intervention characteristics impact the effectiveness of all other interventions. Conclusions: Dietary, physical activity, diet plus physical activity, metformin, and myoinositol interventions reduce the incidence of GDM compared with control interventions. Group and healthcare facility-based physical activity interventions show better effectiveness in preventing GDM than individual and community-based interventions. Other intervention characteristics (e.g. utilization of e-health) don’t impact the effectiveness of lifestyle interventions, and thus, interventions may require consideration of the local context.
AB - Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the implementation of GDM prevention interventions. Methods: Ovid, MEDLINE/PubMed, and EMBASE databases were searched. The Template for Intervention Description and Replication (TIDieR) framework was used to examine intervention characteristics (who, what, when, where, and how). Subgroup analysis was performed by intervention characteristics. Results: 116 studies involving 40,940 participants are included. Group-based physical activity interventions (RR 0.66; 95% CI 0.46, 0.95) reduce the incidence of GDM compared with individual or mixed (individual and group) delivery format (subgroup p-value = 0.04). Physical activity interventions delivered at healthcare facilities reduce the risk of GDM (RR 0.59; 95% CI 0.49, 0.72) compared with home-based interventions (subgroup p-value = 0.03). No other intervention characteristics impact the effectiveness of all other interventions. Conclusions: Dietary, physical activity, diet plus physical activity, metformin, and myoinositol interventions reduce the incidence of GDM compared with control interventions. Group and healthcare facility-based physical activity interventions show better effectiveness in preventing GDM than individual and community-based interventions. Other intervention characteristics (e.g. utilization of e-health) don’t impact the effectiveness of lifestyle interventions, and thus, interventions may require consideration of the local context.
UR - https://www.scopus.com/pages/publications/85204733185
U2 - 10.1038/s43856-024-00491-1
DO - 10.1038/s43856-024-00491-1
M3 - Journal article
C2 - 38643248
AN - SCOPUS:85204733185
SN - 2730-664X
VL - 4
JO - Communications medicine
JF - Communications medicine
IS - 1
M1 - 75
ER -