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Effect of two different nutritional supplements on postprandial glucose response and energy- and protein intake in hospitalised patients with COPD: A randomised cross-over study

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Ingadottir, AR, Bjorgvinsdottir, EB, Beck, AM, Baldwin, C, Weekes, CE, Geirsdottir, OG, Ramel, A, Birgisdottir, BE, Gislason, T & Gunnarsdottir, I 2020, 'Effect of two different nutritional supplements on postprandial glucose response and energy- and protein intake in hospitalised patients with COPD: A randomised cross-over study', Clinical Nutrition, vol. 39, no. 4, 39, pp. 1085-1091. https://doi.org/10.1016/j.clnu.2019.04.010

APA

Ingadottir, A. R., Bjorgvinsdottir, E. B., Beck, A. M., Baldwin, C., Weekes, C. E., Geirsdottir, O. G., Ramel, A., Birgisdottir, B. E., Gislason, T., & Gunnarsdottir, I. (2020). Effect of two different nutritional supplements on postprandial glucose response and energy- and protein intake in hospitalised patients with COPD: A randomised cross-over study. Clinical Nutrition, 39(4), 1085-1091. [39]. https://doi.org/10.1016/j.clnu.2019.04.010

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Author

Ingadottir, Arora Ros ; Bjorgvinsdottir, Eva Bjorg ; Beck, Anne Marie ; Baldwin, Christine ; Weekes, C Elizabeth ; Geirsdottir, Olof Gudny ; Ramel, Alfons ; Birgisdottir, Bryndis Eva ; Gislason, Thorarinn ; Gunnarsdottir, Ingibjorg. / Effect of two different nutritional supplements on postprandial glucose response and energy- and protein intake in hospitalised patients with COPD : A randomised cross-over study. In: Clinical Nutrition. 2020 ; Vol. 39, No. 4. pp. 1085-1091.

Bibtex

@article{0579698872ab4bc9b8aff98d5501f6f4,
title = "Effect of two different nutritional supplements on postprandial glucose response and energy- and protein intake in hospitalised patients with COPD: A randomised cross-over study",
abstract = "INTRODUCTION: Oral nutrition support is frequently used in treatment of malnutrition in patients with chronic obstructive pulmonary disease (COPD). Considering the use of corticoidsteroids in patients with COPD, little is known about the effect on postprandial glucose response and if they might interfere with glucose control. Our aims were to compare the effect of a liquid oral nutritional supplement (ONS) and semi solid inbetween meal snack (snack) on postprandial glucose and energy- and protein intake, and to compare the effect of timing of each intervention on postprandial glucose and energy- and protein intake.METHODS: Patients with COPD (n = 17) admitted to the Department of Pulmonary Medicine, Iceland and defined as at low or medium nutritional risk (score 0-3) were recruited. In a randomised cross-over design, subjects consumed ONS or snack either in a fasting state (study 1) or following breakfast (study 2) and postprandial glucose responses were assessed at regular intervals for two hours (t = 15, t = 30, t = 45, t = 60, t = 90, t = 120 min). Energy- and protein intake was estimated using a validated plate diagram sheet. Wilcoxon Signed-Rank test was used to compare the two interventions.RESULTS: In study 2, following breakfast, postprandial glucose was significantly higher after consuming ONS than the snack after 60 min (9.7 ± 2.4 mmol/L vs. 8.2 ± 3.2 mmol/L, p = 0.013 and 120 min 9.2 ± 3.2 mmol/L vs. 7.9 ± 2.4 mmol/L, p = 0.021, respectively). No difference was found in postprandial glucose concentrations between ONS and the snack when consumed after overnight fasting (study 1). No difference in energy or protein intake from hospital food was seen between supplement types neither in study 1 or 2.CONCLUSION: Lower postprandial glucose concentrations were associated with the snack compared to ONS when taken after a meal compared to either type directly after overnight fasting. The clinical relevance of higher postprandial blood glucose after consuming a liquid ONS after breakfast compared with a semi solid snack needs to be studied further.",
keywords = "COPD, Energy intake, Hospitalized, In-between meal snacks, Oral nutrition supplements, Protein intake",
author = "Ingadottir, {Arora Ros} and Bjorgvinsdottir, {Eva Bjorg} and Beck, {Anne Marie} and Christine Baldwin and Weekes, {C Elizabeth} and Geirsdottir, {Olof Gudny} and Alfons Ramel and Birgisdottir, {Bryndis Eva} and Thorarinn Gislason and Ingibjorg Gunnarsdottir",
note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2020",
month = apr,
doi = "10.1016/j.clnu.2019.04.010",
language = "English",
volume = "39",
pages = "1085--1091",
journal = "Clinical Nutrition",
issn = "0261-5614",
publisher = "Elsevier BV",
number = "4",

}

RIS

TY - JOUR

T1 - Effect of two different nutritional supplements on postprandial glucose response and energy- and protein intake in hospitalised patients with COPD

T2 - A randomised cross-over study

AU - Ingadottir, Arora Ros

AU - Bjorgvinsdottir, Eva Bjorg

AU - Beck, Anne Marie

AU - Baldwin, Christine

AU - Weekes, C Elizabeth

AU - Geirsdottir, Olof Gudny

AU - Ramel, Alfons

AU - Birgisdottir, Bryndis Eva

AU - Gislason, Thorarinn

AU - Gunnarsdottir, Ingibjorg

N1 - Publisher Copyright: © 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/4

Y1 - 2020/4

N2 - INTRODUCTION: Oral nutrition support is frequently used in treatment of malnutrition in patients with chronic obstructive pulmonary disease (COPD). Considering the use of corticoidsteroids in patients with COPD, little is known about the effect on postprandial glucose response and if they might interfere with glucose control. Our aims were to compare the effect of a liquid oral nutritional supplement (ONS) and semi solid inbetween meal snack (snack) on postprandial glucose and energy- and protein intake, and to compare the effect of timing of each intervention on postprandial glucose and energy- and protein intake.METHODS: Patients with COPD (n = 17) admitted to the Department of Pulmonary Medicine, Iceland and defined as at low or medium nutritional risk (score 0-3) were recruited. In a randomised cross-over design, subjects consumed ONS or snack either in a fasting state (study 1) or following breakfast (study 2) and postprandial glucose responses were assessed at regular intervals for two hours (t = 15, t = 30, t = 45, t = 60, t = 90, t = 120 min). Energy- and protein intake was estimated using a validated plate diagram sheet. Wilcoxon Signed-Rank test was used to compare the two interventions.RESULTS: In study 2, following breakfast, postprandial glucose was significantly higher after consuming ONS than the snack after 60 min (9.7 ± 2.4 mmol/L vs. 8.2 ± 3.2 mmol/L, p = 0.013 and 120 min 9.2 ± 3.2 mmol/L vs. 7.9 ± 2.4 mmol/L, p = 0.021, respectively). No difference was found in postprandial glucose concentrations between ONS and the snack when consumed after overnight fasting (study 1). No difference in energy or protein intake from hospital food was seen between supplement types neither in study 1 or 2.CONCLUSION: Lower postprandial glucose concentrations were associated with the snack compared to ONS when taken after a meal compared to either type directly after overnight fasting. The clinical relevance of higher postprandial blood glucose after consuming a liquid ONS after breakfast compared with a semi solid snack needs to be studied further.

AB - INTRODUCTION: Oral nutrition support is frequently used in treatment of malnutrition in patients with chronic obstructive pulmonary disease (COPD). Considering the use of corticoidsteroids in patients with COPD, little is known about the effect on postprandial glucose response and if they might interfere with glucose control. Our aims were to compare the effect of a liquid oral nutritional supplement (ONS) and semi solid inbetween meal snack (snack) on postprandial glucose and energy- and protein intake, and to compare the effect of timing of each intervention on postprandial glucose and energy- and protein intake.METHODS: Patients with COPD (n = 17) admitted to the Department of Pulmonary Medicine, Iceland and defined as at low or medium nutritional risk (score 0-3) were recruited. In a randomised cross-over design, subjects consumed ONS or snack either in a fasting state (study 1) or following breakfast (study 2) and postprandial glucose responses were assessed at regular intervals for two hours (t = 15, t = 30, t = 45, t = 60, t = 90, t = 120 min). Energy- and protein intake was estimated using a validated plate diagram sheet. Wilcoxon Signed-Rank test was used to compare the two interventions.RESULTS: In study 2, following breakfast, postprandial glucose was significantly higher after consuming ONS than the snack after 60 min (9.7 ± 2.4 mmol/L vs. 8.2 ± 3.2 mmol/L, p = 0.013 and 120 min 9.2 ± 3.2 mmol/L vs. 7.9 ± 2.4 mmol/L, p = 0.021, respectively). No difference was found in postprandial glucose concentrations between ONS and the snack when consumed after overnight fasting (study 1). No difference in energy or protein intake from hospital food was seen between supplement types neither in study 1 or 2.CONCLUSION: Lower postprandial glucose concentrations were associated with the snack compared to ONS when taken after a meal compared to either type directly after overnight fasting. The clinical relevance of higher postprandial blood glucose after consuming a liquid ONS after breakfast compared with a semi solid snack needs to be studied further.

KW - COPD

KW - Energy intake

KW - Hospitalized

KW - In-between meal snacks

KW - Oral nutrition supplements

KW - Protein intake

UR - http://www.scopus.com/inward/record.url?scp=85064996349&partnerID=8YFLogxK

U2 - 10.1016/j.clnu.2019.04.010

DO - 10.1016/j.clnu.2019.04.010

M3 - Journal article

C2 - 31064666

VL - 39

SP - 1085

EP - 1091

JO - Clinical Nutrition

JF - Clinical Nutrition

SN - 0261-5614

IS - 4

M1 - 39

ER -

ID: 57923804