Effect of surgery on sensory threshold and somatosensory evoked potentials after skin stimulation.

C Lund, O B Hansen, H Kehlet

16 Citations (Scopus)

Abstract

We have studied the effect of surgical injury on cutaneous sensitivity and somatosensory evoked potentials (SSEP) to dermatomal electrical stimulation in 10 patients undergoing hysterectomy. Forty-eight hours after surgery, sensory threshold increased from 2.2 (SEM 0.3) mA to 4.4 (1.1) mA (P less than 0.01) and SSEP amplitudes in P1, N1, P2 and the peak-to-peak amplitudes decreased (P less than 0.05). Latency was prolonged only in the N3 component (P less than 0.05). No changes were seen in threshold and SSEP in a control group studied over the same interval. The results suggest that surgical injury activates antinociceptive modulatory systems.
Translated title of the contributionEffect of surgery on sensory threshold and somatosensory evoked potentials after skin stimulation.
Original languageEnglish
JournalBritish Journal of Anaesthesia
Volume65
Issue number2
Pages (from-to)173-176
Number of pages4
ISSN0007-0912
Publication statusPublished - 1990

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