Effect of nateglinide on the incidence of diabetes and cardiovascular events

Rury R Holman; Steven M Haffner; John J McMurray; M Angelyn Bethel; Björn Holzhauer; Tsushung A Hua; Yuri Belenkov; Mitradev Boolell; John B Buse; Brendan M Buckley; Antonio R Chacra; Fu-Tien Chiang; Bernard Charbonnel; Chun-Chung Chow; Melanie J Davies; Prakash Deedwania; Peter Diem; Daniel Einhorn; Vivian Fonseca; Gregory R Fulcher; Zbigniew Gaciong; Sonia Gaztambide; Thomas Giles; Edward Horton; Hasan Ilkova; Trond Jenssen; Steven E Kahn; Henry Krum; Markku Laakso; Lawrence A Leiter; Naomi S Levitt; Viacheslav Mareev; Felipe Martinez; Chantal Masson; Theodore Mazzone; Eduardo Meaney; Richard Nesto; Changyu Pan; Rudolf Prager; Sotirios A Raptis; Guy E H M Rutten; Herbert Sandstroem; Frank Schaper; Andre Scheen; Ole Schmitz; Isaac Sinay; Vladimir Soska; Steen Stender; Gyula Tamás; Gianni Tognoni; NAVIGATOR Study Group

doi:10.1056/NEJMoa1001122

Effect of nateglinide on the incidence of diabetes and cardiovascular events

Rury R Holman, Steven M Haffner, John J McMurray, M Angelyn Bethel, Björn Holzhauer, Tsushung A Hua, Yuri Belenkov, Mitradev Boolell, John B Buse, Brendan M Buckley, Antonio R Chacra, Fu-Tien Chiang, Bernard Charbonnel, Chun-Chung Chow, Melanie J Davies, Prakash Deedwania, Peter Diem, Daniel Einhorn, Vivian Fonseca, Gregory R FulcherZbigniew Gaciong, Sonia Gaztambide, Thomas Giles, Edward Horton, Hasan Ilkova, Trond Jenssen, Steven E Kahn, Henry Krum, Markku Laakso, Lawrence A Leiter, Naomi S Levitt, Viacheslav Mareev, Felipe Martinez, Chantal Masson, Theodore Mazzone, Eduardo Meaney, Richard Nesto, Changyu Pan, Rudolf Prager, Sotirios A Raptis, Guy E H M Rutten, Herbert Sandstroem, Frank Schaper, Andre Scheen, Ole Schmitz, Isaac Sinay, Vladimir Soska, Steen Stender, Gyula Tamás, Gianni Tognoni, NAVIGATOR Study Group

477 Citations (Scopus)

Abstract

The ability of short-acting insulin secretagogues to reduce the risk of diabetes or cardiovascular events in people with impaired glucose tolerance is unknown.

Original language	English
Journal	New England Journal of Medicine
Volume	362
Issue number	16
Pages (from-to)	1463-76
Number of pages	14
ISSN	0028-4793
DOIs	https://doi.org/10.1056/NEJMoa1001122
Publication status	Published - 22 Apr 2010

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Holman, R. R., Haffner, S. M., McMurray, J. J., Bethel, M. A., Holzhauer, B., Hua, T. A., Belenkov, Y., Boolell, M., Buse, J. B., Buckley, B. M., Chacra, A. R., Chiang, F.-T., Charbonnel, B., Chow, C.-C., Davies, M. J., Deedwania, P., Diem, P., Einhorn, D., Fonseca, V., ... NAVIGATOR Study Group (2010). Effect of nateglinide on the incidence of diabetes and cardiovascular events. New England Journal of Medicine, 362(16), 1463-76. https://doi.org/10.1056/NEJMoa1001122

Holman, RR, Haffner, SM, McMurray, JJ, Bethel, MA, Holzhauer, B, Hua, TA, Belenkov, Y, Boolell, M, Buse, JB, Buckley, BM, Chacra, AR, Chiang, F-T, Charbonnel, B, Chow, C-C, Davies, MJ, Deedwania, P, Diem, P, Einhorn, D, Fonseca, V, Fulcher, GR, Gaciong, Z, Gaztambide, S, Giles, T, Horton, E, Ilkova, H, Jenssen, T, Kahn, SE, Krum, H, Laakso, M, Leiter, LA, Levitt, NS, Mareev, V, Martinez, F, Masson, C, Mazzone, T, Meaney, E, Nesto, R, Pan, C, Prager, R, Raptis, SA, Rutten, GEHM, Sandstroem, H, Schaper, F, Scheen, A, Schmitz, O, Sinay, I, Soska, V, Stender, S, Tamás, G, Tognoni, G & NAVIGATOR Study Group 2010, 'Effect of nateglinide on the incidence of diabetes and cardiovascular events', New England Journal of Medicine, vol. 362, no. 16, pp. 1463-76. https://doi.org/10.1056/NEJMoa1001122

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title = "Effect of nateglinide on the incidence of diabetes and cardiovascular events",

abstract = "The ability of short-acting insulin secretagogues to reduce the risk of diabetes or cardiovascular events in people with impaired glucose tolerance is unknown.",

author = "Holman, \{Rury R\} and Haffner, \{Steven M\} and McMurray, \{John J\} and Bethel, \{M Angelyn\} and Bj{\"o}rn Holzhauer and Hua, \{Tsushung A\} and Yuri Belenkov and Mitradev Boolell and Buse, \{John B\} and Buckley, \{Brendan M\} and Chacra, \{Antonio R\} and Fu-Tien Chiang and Bernard Charbonnel and Chun-Chung Chow and Davies, \{Melanie J\} and Prakash Deedwania and Peter Diem and Daniel Einhorn and Vivian Fonseca and Fulcher, \{Gregory R\} and Zbigniew Gaciong and Sonia Gaztambide and Thomas Giles and Edward Horton and Hasan Ilkova and Trond Jenssen and Kahn, \{Steven E\} and Henry Krum and Markku Laakso and Leiter, \{Lawrence A\} and Levitt, \{Naomi S\} and Viacheslav Mareev and Felipe Martinez and Chantal Masson and Theodore Mazzone and Eduardo Meaney and Richard Nesto and Changyu Pan and Rudolf Prager and Raptis, \{Sotirios A\} and Rutten, \{Guy E H M\} and Herbert Sandstroem and Frank Schaper and Andre Scheen and Ole Schmitz and Isaac Sinay and Vladimir Soska and Steen Stender and Gyula Tam{\'a}s and Gianni Tognoni and \{NAVIGATOR Study Group\}",

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AU - Chacra, Antonio R

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AU - Deedwania, Prakash

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AU - Fonseca, Vivian

AU - Fulcher, Gregory R

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AU - Giles, Thomas

AU - Horton, Edward

AU - Ilkova, Hasan

AU - Jenssen, Trond

AU - Kahn, Steven E

AU - Krum, Henry

AU - Laakso, Markku

AU - Leiter, Lawrence A

AU - Levitt, Naomi S

AU - Mareev, Viacheslav

AU - Martinez, Felipe

AU - Masson, Chantal

AU - Mazzone, Theodore

AU - Meaney, Eduardo

AU - Nesto, Richard

AU - Pan, Changyu

AU - Prager, Rudolf

AU - Raptis, Sotirios A

AU - Rutten, Guy E H M

AU - Sandstroem, Herbert

AU - Schaper, Frank

AU - Scheen, Andre

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AU - Sinay, Isaac

AU - Soska, Vladimir

AU - Stender, Steen

AU - Tamás, Gyula

AU - Tognoni, Gianni

AU - NAVIGATOR Study Group

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N2 - The ability of short-acting insulin secretagogues to reduce the risk of diabetes or cardiovascular events in people with impaired glucose tolerance is unknown.

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SP - 1463

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JF - New England Journal of Medicine

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Effect of nateglinide on the incidence of diabetes and cardiovascular events

Abstract

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