Effect of donepezil on emergence of apathy in mild to moderate Alzheimer's disease

Gunhild Waldemar; Serge Gauthier; Roy Jones; David Wilkinson; Jeffrey Cummings; Oscar Lopez; Richard Zhang; Yikang Xu; Yijun Sun; Sean Knox; Sharon Richardson; Joan Mackell

doi:10.1002/gps.2507

Effect of donepezil on emergence of apathy in mild to moderate Alzheimer's disease

Gunhild Waldemar, Serge Gauthier, Roy Jones, David Wilkinson, Jeffrey Cummings, Oscar Lopez, Richard Zhang, Yikang Xu, Yijun Sun, Sean Knox, Sharon Richardson, Joan Mackell

Department of Neurology

48 Citations (Scopus)

Abstract

To determine whether donepezil treatment (10 mg/day over 24 weeks) is associated with delayed emergence of apathy in patients with mild to moderate Alzheimer's disease (AD) and to explore relationships between donepezil's effects on apathy and other Neuropsychiatric Inventory (NPI)-measured behavioural symptoms.

Original language	English
Journal	International Journal of Geriatric Psychiatry
Volume	26
Issue number	2
Pages (from-to)	150-7
Number of pages	8
ISSN	0885-6230
DOIs	https://doi.org/10.1002/gps.2507
Publication status	Published - 2011

Keywords

Aged
Aged, 80 and over
Alzheimer Disease
Apathy
Brief Psychiatric Rating Scale
Cholinesterase Inhibitors
Female
Humans
Indans
Male
Middle Aged
Nootropic Agents
Piperidines
Severity of Illness Index

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10.1002/gps.2507

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title = "Effect of donepezil on emergence of apathy in mild to moderate Alzheimer's disease",

abstract = "To determine whether donepezil treatment (10 mg/day over 24 weeks) is associated with delayed emergence of apathy in patients with mild to moderate Alzheimer's disease (AD) and to explore relationships between donepezil's effects on apathy and other Neuropsychiatric Inventory (NPI)-measured behavioural symptoms.",

keywords = "Aged, Aged, 80 and over, Alzheimer Disease, Apathy, Brief Psychiatric Rating Scale, Cholinesterase Inhibitors, Female, Humans, Indans, Male, Middle Aged, Nootropic Agents, Piperidines, Severity of Illness Index",

author = "Gunhild Waldemar and Serge Gauthier and Roy Jones and David Wilkinson and Jeffrey Cummings and Oscar Lopez and Richard Zhang and Yikang Xu and Yijun Sun and Sean Knox and Sharon Richardson and Joan Mackell",

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year = "2011",

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T1 - Effect of donepezil on emergence of apathy in mild to moderate Alzheimer's disease

AU - Waldemar, Gunhild

AU - Gauthier, Serge

AU - Jones, Roy

AU - Wilkinson, David

AU - Cummings, Jeffrey

AU - Lopez, Oscar

AU - Zhang, Richard

AU - Xu, Yikang

AU - Sun, Yijun

AU - Knox, Sean

AU - Richardson, Sharon

AU - Mackell, Joan

PY - 2011

Y1 - 2011

N2 - To determine whether donepezil treatment (10 mg/day over 24 weeks) is associated with delayed emergence of apathy in patients with mild to moderate Alzheimer's disease (AD) and to explore relationships between donepezil's effects on apathy and other Neuropsychiatric Inventory (NPI)-measured behavioural symptoms.

AB - To determine whether donepezil treatment (10 mg/day over 24 weeks) is associated with delayed emergence of apathy in patients with mild to moderate Alzheimer's disease (AD) and to explore relationships between donepezil's effects on apathy and other Neuropsychiatric Inventory (NPI)-measured behavioural symptoms.

KW - Aged

KW - Aged, 80 and over

KW - Alzheimer Disease

KW - Apathy

KW - Brief Psychiatric Rating Scale

KW - Cholinesterase Inhibitors

KW - Female

KW - Humans

KW - Indans

KW - Male

KW - Middle Aged

KW - Nootropic Agents

KW - Piperidines

KW - Severity of Illness Index

UR - https://www.scopus.com/pages/publications/78651464885

U2 - 10.1002/gps.2507

DO - 10.1002/gps.2507

M3 - Journal article

C2 - 20597141

SN - 0885-6230

VL - 26

SP - 150

EP - 157

JO - International Journal of Geriatric Psychiatry

JF - International Journal of Geriatric Psychiatry

IS - 2

ER -

Effect of donepezil on emergence of apathy in mild to moderate Alzheimer's disease

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Keywords

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