Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study

Birte Nygaard; Ebbe Winther Jensen; Jan Kvetny; Anne Jarløv; Jens Faber

doi:10.1530/EJE-09-0542

Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study

Birte Nygaard, Ebbe Winther Jensen, Jan Kvetny, Anne Jarløv, Jens Faber

116 Citations (Scopus)

Abstract

Treatment of hypothyroidism with 3,5,3'-triiodothyronine (T(3)) is controversial. A recent meta-analysis concludes that no evidence is present in favour of using T(3). However, the analysis included a mixture of different patient groups and dose-regimens.

Original language	English
Journal	European Journal of Endocrinology
Volume	161
Issue number	6
Pages (from-to)	895-902
Number of pages	8
ISSN	0804-4643
DOIs	https://doi.org/10.1530/EJE-09-0542
Publication status	Published - 2009

Keywords

Adolescent
Adult
Aged
Antithyroid Agents
Cross-Over Studies
Depression
Drug Therapy, Combination
Female
Humans
Hypothyroidism
Male
Middle Aged
Quality of Life
Thyrotropin
Thyroxine
Triiodothyronine

Access to Document

10.1530/EJE-09-0542

Cite this

Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study. / Nygaard, Birte; Jensen, Ebbe Winther; Kvetny, Jan et al.
In: European Journal of Endocrinology, Vol. 161, No. 6, 2009, p. 895-902.

Research output: Contribution to journal › Journal article › Research › peer-review

@article{034bf30972ef41a283106da77363b5cb,

title = "Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study",

abstract = "Treatment of hypothyroidism with 3,5,3'-triiodothyronine (T(3)) is controversial. A recent meta-analysis concludes that no evidence is present in favour of using T(3). However, the analysis included a mixture of different patient groups and dose-regimens.",

keywords = "Adolescent, Adult, Aged, Antithyroid Agents, Cross-Over Studies, Depression, Drug Therapy, Combination, Female, Humans, Hypothyroidism, Male, Middle Aged, Quality of Life, Thyrotropin, Thyroxine, Triiodothyronine",

author = "Birte Nygaard and Jensen, {Ebbe Winther} and Jan Kvetny and Anne Jarl{\o}v and Jens Faber",

year = "2009",

doi = "10.1530/EJE-09-0542",

language = "English",

volume = "161",

pages = "895--902",

journal = "European Journal of Endocrinology",

issn = "0804-4643",

publisher = "BioScientifica Ltd",

number = "6",

}

TY - JOUR

T1 - Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study

AU - Nygaard, Birte

AU - Jensen, Ebbe Winther

AU - Kvetny, Jan

AU - Jarløv, Anne

AU - Faber, Jens

PY - 2009

Y1 - 2009

N2 - Treatment of hypothyroidism with 3,5,3'-triiodothyronine (T(3)) is controversial. A recent meta-analysis concludes that no evidence is present in favour of using T(3). However, the analysis included a mixture of different patient groups and dose-regimens.

AB - Treatment of hypothyroidism with 3,5,3'-triiodothyronine (T(3)) is controversial. A recent meta-analysis concludes that no evidence is present in favour of using T(3). However, the analysis included a mixture of different patient groups and dose-regimens.

KW - Adolescent

KW - Adult

KW - Aged

KW - Antithyroid Agents

KW - Cross-Over Studies

KW - Depression

KW - Drug Therapy, Combination

KW - Female

KW - Humans

KW - Hypothyroidism

KW - Male

KW - Middle Aged

KW - Quality of Life

KW - Thyrotropin

KW - Thyroxine

KW - Triiodothyronine

U2 - 10.1530/EJE-09-0542

DO - 10.1530/EJE-09-0542

M3 - Journal article

C2 - 19666698

SN - 0804-4643

VL - 161

SP - 895

EP - 902

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

IS - 6

ER -

Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study

Abstract

Keywords

Access to Document

Fingerprint

Cite this