TY - JOUR
T1 - Effect of aerobic exercise training on asthma in adults - A systematic review and meta-analysis
AU - Hansen, Erik Soeren Halvard
AU - Pitzner-Fabricius, Anders
AU - Toennesen, Louise Lindhardt
AU - Rasmusen, Hanne Kruuse
AU - Hostrup, Morten
AU - Hellsten, Ylva
AU - Backer, Vibeke
AU - Henriksen, Marius
N1 - Publisher Copyright:
Copyright © 2020 ERS.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - Objective: To evaluate the effect of aerobic exercise training on asthma control, lung function and airway inflammation in adults with asthma. Design: Systematic review and meta-analysis. Methods: Randomised controlled trials investigating the effect of ≥8 weeks of aerobic exercise training on outcomes for asthma control, lung function and airway inflammation in adults with asthma were eligible for study. MEDLINE, Embase, CINAHL, PEDro and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched up to April 3, 2019. Risk of bias was assessed using the Cochrane Risk of Bias Tool. Results: We included 11 studies with a total of 543 adults with asthma. Participants' mean (range) age was 36.5 (22-54) years; 74.8% of participants were female and the mean (range) body mass index was 27.6 (23.2-38.1) kg·m-2. Interventions had a median (range) duration of 12 (8-12)weeks and included walking, jogging, spinning, treadmill running and other unspecified exercise training programmes. Exercise training improved asthma control with a standard mean difference (SMD) of -0.48 (-0.81 - -0.16). Lung function slightly increased with an SMD of -0.36 (-0.72-0.00) in favour of exercise training. Exercise training had no apparent effect on markers of airway inflammation (SMD -0.03 (-0.41-0.36)). Conclusions: In adults with asthma, aerobic exercise training has potential to improve asthma control and lung function, but not airway inflammation.
AB - Objective: To evaluate the effect of aerobic exercise training on asthma control, lung function and airway inflammation in adults with asthma. Design: Systematic review and meta-analysis. Methods: Randomised controlled trials investigating the effect of ≥8 weeks of aerobic exercise training on outcomes for asthma control, lung function and airway inflammation in adults with asthma were eligible for study. MEDLINE, Embase, CINAHL, PEDro and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched up to April 3, 2019. Risk of bias was assessed using the Cochrane Risk of Bias Tool. Results: We included 11 studies with a total of 543 adults with asthma. Participants' mean (range) age was 36.5 (22-54) years; 74.8% of participants were female and the mean (range) body mass index was 27.6 (23.2-38.1) kg·m-2. Interventions had a median (range) duration of 12 (8-12)weeks and included walking, jogging, spinning, treadmill running and other unspecified exercise training programmes. Exercise training improved asthma control with a standard mean difference (SMD) of -0.48 (-0.81 - -0.16). Lung function slightly increased with an SMD of -0.36 (-0.72-0.00) in favour of exercise training. Exercise training had no apparent effect on markers of airway inflammation (SMD -0.03 (-0.41-0.36)). Conclusions: In adults with asthma, aerobic exercise training has potential to improve asthma control and lung function, but not airway inflammation.
U2 - 10.1183/13993003.00146-2020
DO - 10.1183/13993003.00146-2020
M3 - Review
C2 - 32350100
SN - 0904-1850
VL - 56
SP - 2000146
JO - European Respiratory Journal. Supplement
JF - European Respiratory Journal. Supplement
IS - 1
ER -