Early diagnosis and treatment for intussusception in children is mandatory

Martin Kobborg; Kristine Bach Korsholm Knudsen; Inge Boetker Rasmussen Ifaoui; Lars Rasmussen; Niels Qvist; Mark Bremholm Ellebæk

Early diagnosis and treatment for intussusception in children is mandatory

Martin Kobborg, Kristine Bach Korsholm Knudsen, Inge Boetker Rasmussen Ifaoui, Lars Rasmussen, Niels Qvist, Mark Bremholm Ellebæk

Abstract

INTRODUCTION: In some cases, surgical treatment is necessary to manage intussusception despite advances in enema reduction. The purpose of this study was to analyse treatment in two tertiary referral university centres for paediatric surgery to identify time-related factors influencing treatment of intussusception.

METHODS: This was a retrospective two-centre chart review, performed for all patients under the age of 16 years who underwent treatment for intussusception during the period from 2005 to 2015. Demographic data and data on different time intervals from symptom debut to end of treatment and compliacations were retrieved from the medical record.

RESULTS: A total of 158 children were included. Non-surgical reduction was used as the primary treatment modality in 48% and intussusception was successfully reduced in 32% of these cases. The non-surgical success rate was found to be significantly higher when the diagnosis was confirmed within four hours of hospitalisation (p = 0.003). A lower rate of bowel resection was observed when the diagnosis was confirmed within four hours of hospitalisation (p = 0.026) and treatment was initiated within six hours of hospitalisation (p = 0.033).

CONCLUSIONS: This study found a relatively low utilisation rate for enema reduction and an overall low enema success rate. The success rate of enema was significantly higher and the intestinal resection rate lower when the diagnosis was confirmed within four hours of hospitalisation, which underpins the importance of a quick and timely diagnosis.

FUNDING: none.

TRIAL REGISTRATION: not relevant.

Original language	English
Journal	Danish Medical Journal
Volume	68
Issue number	3
Pages (from-to)	A09200680
ISSN	1603-9629
Publication status	Published - 16 Feb 2021

Keywords

Adolescent
Child
Early Diagnosis
Enema
Humans
Infant
Intussusception/diagnosis
Retrospective Studies
Treatment Outcome

Cite this

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title = "Early diagnosis and treatment for intussusception in children is mandatory",

abstract = "INTRODUCTION: In some cases, surgical treatment is necessary to manage intussusception despite advances in enema reduction. The purpose of this study was to analyse treatment in two tertiary referral university centres for paediatric surgery to identify time-related factors influencing treatment of intussusception.METHODS: This was a retrospective two-centre chart review, performed for all patients under the age of 16 years who underwent treatment for intussusception during the period from 2005 to 2015. Demographic data and data on different time intervals from symptom debut to end of treatment and compliacations were retrieved from the medical record.RESULTS: A total of 158 children were included. Non-surgical reduction was used as the primary treatment modality in 48% and intussusception was successfully reduced in 32% of these cases. The non-surgical success rate was found to be significantly higher when the diagnosis was confirmed within four hours of hospitalisation (p = 0.003). A lower rate of bowel resection was observed when the diagnosis was confirmed within four hours of hospitalisation (p = 0.026) and treatment was initiated within six hours of hospitalisation (p = 0.033).CONCLUSIONS: This study found a relatively low utilisation rate for enema reduction and an overall low enema success rate. The success rate of enema was significantly higher and the intestinal resection rate lower when the diagnosis was confirmed within four hours of hospitalisation, which underpins the importance of a quick and timely diagnosis.FUNDING: none.TRIAL REGISTRATION: not relevant.",

keywords = "Adolescent, Child, Early Diagnosis, Enema, Humans, Infant, Intussusception/diagnosis, Retrospective Studies, Treatment Outcome",

author = "Martin Kobborg and Knudsen, {Kristine Bach Korsholm} and Ifaoui, {Inge Boetker Rasmussen} and Lars Rasmussen and Niels Qvist and Elleb{\ae}k, {Mark Bremholm}",

note = "Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.",

year = "2021",

month = feb,

day = "16",

language = "English",

volume = "68",

pages = "A09200680",

journal = "Danish Medical Journal",

issn = "1603-9629",

publisher = "Almindelige Danske Laegeforening",

number = "3",

}

TY - JOUR

T1 - Early diagnosis and treatment for intussusception in children is mandatory

AU - Kobborg, Martin

AU - Knudsen, Kristine Bach Korsholm

AU - Ifaoui, Inge Boetker Rasmussen

AU - Rasmussen, Lars

AU - Qvist, Niels

AU - Ellebæk, Mark Bremholm

N1 - Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

PY - 2021/2/16

Y1 - 2021/2/16

N2 - INTRODUCTION: In some cases, surgical treatment is necessary to manage intussusception despite advances in enema reduction. The purpose of this study was to analyse treatment in two tertiary referral university centres for paediatric surgery to identify time-related factors influencing treatment of intussusception.METHODS: This was a retrospective two-centre chart review, performed for all patients under the age of 16 years who underwent treatment for intussusception during the period from 2005 to 2015. Demographic data and data on different time intervals from symptom debut to end of treatment and compliacations were retrieved from the medical record.RESULTS: A total of 158 children were included. Non-surgical reduction was used as the primary treatment modality in 48% and intussusception was successfully reduced in 32% of these cases. The non-surgical success rate was found to be significantly higher when the diagnosis was confirmed within four hours of hospitalisation (p = 0.003). A lower rate of bowel resection was observed when the diagnosis was confirmed within four hours of hospitalisation (p = 0.026) and treatment was initiated within six hours of hospitalisation (p = 0.033).CONCLUSIONS: This study found a relatively low utilisation rate for enema reduction and an overall low enema success rate. The success rate of enema was significantly higher and the intestinal resection rate lower when the diagnosis was confirmed within four hours of hospitalisation, which underpins the importance of a quick and timely diagnosis.FUNDING: none.TRIAL REGISTRATION: not relevant.

AB - INTRODUCTION: In some cases, surgical treatment is necessary to manage intussusception despite advances in enema reduction. The purpose of this study was to analyse treatment in two tertiary referral university centres for paediatric surgery to identify time-related factors influencing treatment of intussusception.METHODS: This was a retrospective two-centre chart review, performed for all patients under the age of 16 years who underwent treatment for intussusception during the period from 2005 to 2015. Demographic data and data on different time intervals from symptom debut to end of treatment and compliacations were retrieved from the medical record.RESULTS: A total of 158 children were included. Non-surgical reduction was used as the primary treatment modality in 48% and intussusception was successfully reduced in 32% of these cases. The non-surgical success rate was found to be significantly higher when the diagnosis was confirmed within four hours of hospitalisation (p = 0.003). A lower rate of bowel resection was observed when the diagnosis was confirmed within four hours of hospitalisation (p = 0.026) and treatment was initiated within six hours of hospitalisation (p = 0.033).CONCLUSIONS: This study found a relatively low utilisation rate for enema reduction and an overall low enema success rate. The success rate of enema was significantly higher and the intestinal resection rate lower when the diagnosis was confirmed within four hours of hospitalisation, which underpins the importance of a quick and timely diagnosis.FUNDING: none.TRIAL REGISTRATION: not relevant.

KW - Adolescent

KW - Child

KW - Early Diagnosis

KW - Enema

KW - Humans

KW - Infant

KW - Intussusception/diagnosis

KW - Retrospective Studies

KW - Treatment Outcome

M3 - Journal article

C2 - 33660607

SN - 1603-9629

VL - 68

SP - A09200680

JO - Danish Medical Journal

JF - Danish Medical Journal

IS - 3

ER -

Early diagnosis and treatment for intussusception in children is mandatory

Abstract

Keywords

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