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Dysbiosis of the Microbiota in Anorexia Nervosa: Pathophysiological Implications

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Anorexia nervosa (AN) is a severe and often enduring condition of which the etiology is unknown. Studies on the gut microbiota in AN have found deviations from that of healthy individuals, which may imply a relation to pathophysiology, development and maintenance of the disorder via the gut-brain axis, which has been shown in other disorders. A narrative review of the gut microbiota studies in AN is presented. Several studies point to a dysbiosis in AN which may have implications for maintenance of a low body weight, immunological changes and a severely reduced food intake. An association may be found to clinical symptoms in AN. A pathophysiological model for disease is presented implying a role of the microbiota in maintenance of AN. Dysbiosis in AN may play an important role in the development and maintenance of AN.
Original languageEnglish
Title of host publicationAnorexia and Bulimia Nervosa
Place of PublicationLondon, UK
PublisherInTech Open Access Publisher
Publication date18 Mar 2019
Publication statusPublished - 18 Mar 2019

ID: 56917506