Dopamine transporter imaging and the effects of deep brain stimulation in patients with Parkinson's disease

A Lokkegaard; L M Werdelin; L Regeur; M Karlsborg; S R Jensen; E Brødsgaard; F F Madsen; M N Lonsdale; L Friberg

doi:10.1007/s00259-006-0257-5

Dopamine transporter imaging and the effects of deep brain stimulation in patients with Parkinson's disease

A Lokkegaard, L M Werdelin, L Regeur, M Karlsborg, S R Jensen, E Brødsgaard, F F Madsen, M N Lonsdale, L Friberg

24 Citations (Scopus)

Abstract

Single-photon emission computed tomography (SPECT) with [123I]FP-CIT is a marker for loss of presynaptic dopamine transporters in the striatum in Parkinson's disease (PD). We used [123I]FP-CIT SPECT in order to evaluate binding to the dopamine transporter before and after neurosurgical treatment with bilateral stimulation in the subthalamic nucleus (STN).

Original language	English
Journal	European Journal of Nuclear Medicine and Molecular Imaging
Volume	34
Issue number	4
Pages (from-to)	508-16
Number of pages	9
ISSN	1619-7070
DOIs	https://doi.org/10.1007/s00259-006-0257-5
Publication status	Published - Apr 2007

Keywords

Adult
Aged
Corpus Striatum
Deep Brain Stimulation
Dopamine Plasma Membrane Transport Proteins
Female
Humans
Male
Middle Aged
Parkinson Disease
Radiopharmaceuticals
Treatment Outcome
Tropanes

Access to Document

10.1007/s00259-006-0257-5

Cite this

Lokkegaard, A., Werdelin, L. M., Regeur, L., Karlsborg, M., Jensen, S. R., Brødsgaard, E., Madsen, F. F., Lonsdale, M. N., & Friberg, L. (2007). Dopamine transporter imaging and the effects of deep brain stimulation in patients with Parkinson's disease. European Journal of Nuclear Medicine and Molecular Imaging, 34(4), 508-16. https://doi.org/10.1007/s00259-006-0257-5

@article{ea5d7d1afa824bf287f1179e28d853d8,

title = "Dopamine transporter imaging and the effects of deep brain stimulation in patients with Parkinson's disease",

abstract = "Single-photon emission computed tomography (SPECT) with [123I]FP-CIT is a marker for loss of presynaptic dopamine transporters in the striatum in Parkinson's disease (PD). We used [123I]FP-CIT SPECT in order to evaluate binding to the dopamine transporter before and after neurosurgical treatment with bilateral stimulation in the subthalamic nucleus (STN).",

keywords = "Adult, Aged, Corpus Striatum, Deep Brain Stimulation, Dopamine Plasma Membrane Transport Proteins, Female, Humans, Male, Middle Aged, Parkinson Disease, Radiopharmaceuticals, Treatment Outcome, Tropanes",

author = "A Lokkegaard and Werdelin, {L M} and L Regeur and M Karlsborg and Jensen, {S R} and E Br{\o}dsgaard and Madsen, {F F} and Lonsdale, {M N} and L Friberg",

year = "2007",

month = apr,

doi = "10.1007/s00259-006-0257-5",

language = "English",

volume = "34",

pages = "508--16",

journal = "European Journal of Nuclear Medicine and Molecular Imaging",

issn = "1619-7070",

publisher = "Springer",

number = "4",

}

TY - JOUR

T1 - Dopamine transporter imaging and the effects of deep brain stimulation in patients with Parkinson's disease

AU - Lokkegaard, A

AU - Werdelin, L M

AU - Regeur, L

AU - Karlsborg, M

AU - Jensen, S R

AU - Brødsgaard, E

AU - Madsen, F F

AU - Lonsdale, M N

AU - Friberg, L

PY - 2007/4

Y1 - 2007/4

N2 - Single-photon emission computed tomography (SPECT) with [123I]FP-CIT is a marker for loss of presynaptic dopamine transporters in the striatum in Parkinson's disease (PD). We used [123I]FP-CIT SPECT in order to evaluate binding to the dopamine transporter before and after neurosurgical treatment with bilateral stimulation in the subthalamic nucleus (STN).

AB - Single-photon emission computed tomography (SPECT) with [123I]FP-CIT is a marker for loss of presynaptic dopamine transporters in the striatum in Parkinson's disease (PD). We used [123I]FP-CIT SPECT in order to evaluate binding to the dopamine transporter before and after neurosurgical treatment with bilateral stimulation in the subthalamic nucleus (STN).

KW - Adult

KW - Aged

KW - Corpus Striatum

KW - Deep Brain Stimulation

KW - Dopamine Plasma Membrane Transport Proteins

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Parkinson Disease

KW - Radiopharmaceuticals

KW - Treatment Outcome

KW - Tropanes

U2 - 10.1007/s00259-006-0257-5

DO - 10.1007/s00259-006-0257-5

M3 - Journal article

C2 - 17096096

SN - 1619-7070

VL - 34

SP - 508

EP - 516

JO - European Journal of Nuclear Medicine and Molecular Imaging

JF - European Journal of Nuclear Medicine and Molecular Imaging

IS - 4

ER -

Dopamine transporter imaging and the effects of deep brain stimulation in patients with Parkinson's disease

Abstract

Keywords

Access to Document

Fingerprint

Cite this