Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?

Meena Asmar; Michael Bache; Filip Krag Knop; Sten Madsbad; Jens Juul Holst

doi:10.1210/jc.2009-2133

Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?

Meena Asmar, Michael Bache, Filip Krag Knop, Sten Madsbad, Jens Juul Holst

Endocrinology Unit

38 Citations (Scopus)

Abstract

Amylin, cosecreted with insulin, has like glucagon-like peptide-1 (GLP-1) been reported to inhibit glucagon secretion, delay gastric emptying, and reduce appetite and food intake. We investigated whether the effects of GLP-1 on gastric emptying, appetite, and food intake are mediated directly or indirectly via release of amylin.

Original language	English
Journal	The Journal of clinical endocrinology and metabolism
Volume	95
Issue number	5
Pages (from-to)	2367-75
Number of pages	9
DOIs	https://doi.org/10.1210/jc.2009-2133
Publication status	Published - 1 May 2010

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10.1210/jc.2009-2133

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@article{951667efa1404a3496049fe4119a6051,

title = "Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?",

abstract = "Amylin, cosecreted with insulin, has like glucagon-like peptide-1 (GLP-1) been reported to inhibit glucagon secretion, delay gastric emptying, and reduce appetite and food intake. We investigated whether the effects of GLP-1 on gastric emptying, appetite, and food intake are mediated directly or indirectly via release of amylin.",

author = "Meena Asmar and Michael Bache and Knop, \{Filip Krag\} and Sten Madsbad and Holst, \{Jens Juul\}",

year = "2010",

month = may,

day = "1",

doi = "10.1210/jc.2009-2133",

language = "English",

volume = "95",

pages = "2367--75",

journal = "The Journal of clinical endocrinology and metabolism",

issn = "1945-7197",