Abstract
The magnocellular neurons in the hypothalamic paraventricular (PVN) and supraoptic nuclei (SON) either contain vasopressin or oxytocin. Even though both hormones are released after systemic administration of nicotine, the mechanism through which the two populations of neurons are activated is not known. This study was carried out in the rat to investigate the effect of increasing doses of nicotine on subsets of magnocellular neurons containing either oxytocin or vasopressin.
| Original language | English |
|---|---|
| Journal | Endocrine Regulations |
| Volume | 46 |
| Issue number | 1 |
| Pages (from-to) | 13-20 |
| Number of pages | 8 |
| ISSN | 1210-0668 |
| Publication status | Published - 2012 |
Keywords
- Animals
- Drug Evaluation, Preclinical
- Drug Resistance
- Ganglionic Stimulants
- Immunohistochemistry
- Male
- Neurons
- Nicotine
- Oxytocin
- Paraventricular Hypothalamic Nucleus
- Proto-Oncogene Proteins c-fos
- Rats
- Rats, Wistar
- Supraoptic Nucleus
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