Differential nongenetic impact of birth weight versus third-trimester growth velocity on glucose metabolism and magnetic resonance imaging abdominal obesity in young healthy twins

Kasper Pilgaard; Thomas Hammershaimb Mosbech; Louise Groth Grunnet; Hans Rudolf Lytchoff Eiberg; Gerrit Van Hall; Eva Fallentin; Torben Kjeldgaard Larsen; Rasmus Larsen; Pernille Hasse Busk Poulsen; Allan Vaag

doi:10.1210/jc.2011-0577

Differential nongenetic impact of birth weight versus third-trimester growth velocity on glucose metabolism and magnetic resonance imaging abdominal obesity in young healthy twins

Kasper Pilgaard, Thomas Hammershaimb Mosbech, Louise Groth Grunnet, Hans Rudolf Lytchoff Eiberg, Gerrit Van Hall, Eva Fallentin, Torben Kjeldgaard Larsen, Rasmus Larsen, Pernille Hasse Busk Poulsen, Allan Vaag

Department of Diagnostic Radiology

23 Citations (Scopus)

Abstract

Low birth weight is associated with type 2 diabetes, which to some extent may be mediated via abdominal adiposity and insulin resistance. Fetal growth velocity is high during the third trimester, constituting a potential critical window for organ programming. Intra-pair differences among monozygotic twins are instrumental in determining nongenetic associations between early environment and adult metabolic phenotype.

Original language	English
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	96
Issue number	9
Pages (from-to)	2835-43
Number of pages	9
ISSN	0021-972X
DOIs	https://doi.org/10.1210/jc.2011-0577
Publication status	Published - 2011

Keywords

Adolescent
Birth Weight
Body Composition
Female
Glucose
Glucose Clamp Technique
Humans
Infant, Low Birth Weight
Infant, Newborn
Insulin
Insulin Resistance
Male
Obesity, Abdominal
Sex Factors
Twins
Young Adult

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10.1210/jc.2011-0577

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Pilgaard, K., Hammershaimb Mosbech, T., Grunnet, L. G., Eiberg, H. R. L., Van Hall, G., Fallentin, E., Larsen, T. K., Larsen, R., Poulsen, P. H. B., & Vaag, A. (2011). Differential nongenetic impact of birth weight versus third-trimester growth velocity on glucose metabolism and magnetic resonance imaging abdominal obesity in young healthy twins. Journal of Clinical Endocrinology and Metabolism, 96(9), 2835-43. https://doi.org/10.1210/jc.2011-0577

Differential nongenetic impact of birth weight versus third-trimester growth velocity on glucose metabolism and magnetic resonance imaging abdominal obesity in young healthy twins. / Pilgaard, Kasper; Hammershaimb Mosbech, Thomas; Grunnet, Louise Groth et al.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 9, 2011, p. 2835-43.

Research output: Contribution to journal › Journal article › Research › peer-review

Pilgaard, K, Hammershaimb Mosbech, T, Grunnet, LG, Eiberg, HRL, Van Hall, G , Fallentin, E, Larsen, TK, Larsen, R, Poulsen, PHB & Vaag, A 2011, 'Differential nongenetic impact of birth weight versus third-trimester growth velocity on glucose metabolism and magnetic resonance imaging abdominal obesity in young healthy twins', Journal of Clinical Endocrinology and Metabolism, vol. 96, no. 9, pp. 2835-43. https://doi.org/10.1210/jc.2011-0577

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AU - Fallentin, Eva

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Differential nongenetic impact of birth weight versus third-trimester growth velocity on glucose metabolism and magnetic resonance imaging abdominal obesity in young healthy twins

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Keywords

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