Diet and physical activity in Greenland: genetic interactions and associations with obesity and diabetes

Ninna Karsbæk Senftleber; Maria Overvad; Inger Katrine Dahl-Petersen; Peter Bjerregaard; Marit Eika Jørgensen

doi:10.1139/apnm-2021-0020

Diet and physical activity in Greenland: genetic interactions and associations with obesity and diabetes

Ninna Karsbæk Senftleber, Maria Overvad, Inger Katrine Dahl-Petersen, Peter Bjerregaard, Marit Eika Jørgensen

Steno Diabetes Center Copenhagen

17 Citations (Scopus)

Abstract

The Inuit in Greenland have gone through dramatic lifestyle changes during the last half century. More time is spent being sedentary and imported foods replaces traditional foods like seal and whale. The population has also experienced a rapid growth in obesity and metabolic disturbances and diabetes is today common despite being almost unknown few decades ago. In this paper, we describe and discuss the role of lifestyle changes and genetics for Inuit metabolic health. Novelty: Cardiometabolic disease risk has increased in Greenland. Lifestyle changes and possibly gene-lifestyle interactions play a role.

Original language	English
Journal	Applied Physiology, Nutrition and Metabolism
Volume	46
Issue number	8
Pages (from-to)	849-855
Number of pages	7
ISSN	1715-5312
DOIs	https://doi.org/10.1139/apnm-2021-0020
Publication status	Published - Aug 2021

Keywords

Diabetes Mellitus, Type 2/epidemiology
Diet/methods
Exercise
Genetic Predisposition to Disease/epidemiology
Greenland/epidemiology
Health Surveys/methods
Humans
Inuits/statistics & numerical data
Obesity/epidemiology
Sedentary Behavior

Access to Document

10.1139/apnm-2021-0020

Cite this

@article{d21b5d681e074fccbdfb4a0a93fcf720,

title = "Diet and physical activity in Greenland: genetic interactions and associations with obesity and diabetes",

abstract = "The Inuit in Greenland have gone through dramatic lifestyle changes during the last half century. More time is spent being sedentary and imported foods replaces traditional foods like seal and whale. The population has also experienced a rapid growth in obesity and metabolic disturbances and diabetes is today common despite being almost unknown few decades ago. In this paper, we describe and discuss the role of lifestyle changes and genetics for Inuit metabolic health. Novelty: Cardiometabolic disease risk has increased in Greenland. Lifestyle changes and possibly gene-lifestyle interactions play a role.",

keywords = "Diabetes Mellitus, Type 2/epidemiology, Diet/methods, Exercise, Genetic Predisposition to Disease/epidemiology, Greenland/epidemiology, Health Surveys/methods, Humans, Inuits/statistics & numerical data, Obesity/epidemiology, Sedentary Behavior",

author = "Senftleber, {Ninna Karsb{\ae}k} and Maria Overvad and Dahl-Petersen, {Inger Katrine} and Peter Bjerregaard and J{\o}rgensen, {Marit Eika}",

year = "2021",

month = aug,

doi = "10.1139/apnm-2021-0020",

language = "English",

volume = "46",

pages = "849--855",

journal = "Applied Physiology, Nutrition and Metabolism",

issn = "1715-5312",

publisher = "National Research Council of Canada",

number = "8",

}

TY - JOUR

T1 - Diet and physical activity in Greenland

T2 - genetic interactions and associations with obesity and diabetes

AU - Senftleber, Ninna Karsbæk

AU - Overvad, Maria

AU - Dahl-Petersen, Inger Katrine

AU - Bjerregaard, Peter

AU - Jørgensen, Marit Eika

PY - 2021/8

Y1 - 2021/8

N2 - The Inuit in Greenland have gone through dramatic lifestyle changes during the last half century. More time is spent being sedentary and imported foods replaces traditional foods like seal and whale. The population has also experienced a rapid growth in obesity and metabolic disturbances and diabetes is today common despite being almost unknown few decades ago. In this paper, we describe and discuss the role of lifestyle changes and genetics for Inuit metabolic health. Novelty: Cardiometabolic disease risk has increased in Greenland. Lifestyle changes and possibly gene-lifestyle interactions play a role.

AB - The Inuit in Greenland have gone through dramatic lifestyle changes during the last half century. More time is spent being sedentary and imported foods replaces traditional foods like seal and whale. The population has also experienced a rapid growth in obesity and metabolic disturbances and diabetes is today common despite being almost unknown few decades ago. In this paper, we describe and discuss the role of lifestyle changes and genetics for Inuit metabolic health. Novelty: Cardiometabolic disease risk has increased in Greenland. Lifestyle changes and possibly gene-lifestyle interactions play a role.

KW - Diabetes Mellitus, Type 2/epidemiology

KW - Diet/methods

KW - Exercise

KW - Genetic Predisposition to Disease/epidemiology

KW - Greenland/epidemiology

KW - Health Surveys/methods

KW - Humans

KW - Inuits/statistics & numerical data

KW - Obesity/epidemiology

KW - Sedentary Behavior

UR - http://www.scopus.com/inward/record.url?scp=85112281001&partnerID=8YFLogxK

U2 - 10.1139/apnm-2021-0020

DO - 10.1139/apnm-2021-0020

M3 - Review

C2 - 34107227

SN - 1715-5312

VL - 46

SP - 849

EP - 855

JO - Applied Physiology, Nutrition and Metabolism

JF - Applied Physiology, Nutrition and Metabolism

IS - 8

ER -

Diet and physical activity in Greenland: genetic interactions and associations with obesity and diabetes

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this