Diagnostik og behandling af sinonasal cancer

Sinonasal cancer is rare, and the symptoms are often vague leading to a delay in diagnosis which affects the prognosis. This cancer type is most common in elderly men, and it consists of many different histological types, mainly carcinomas. The risk factors remain elusive, except for an association between intestinal type adenocarcinoma and exposure to wood dust. Human papillomavirus may play a role in squamous cell carcinomas. The treatment of choice is surgery, often combined with radiotherapy. Most surgeries are endoscopic (image-guided) to secure complete resection in a complex anatomic region.