Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Diagnostic yield of high-density versus low-density EEG: The effect of spatial sampling, timing and duration of recording

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Steady-state visual evoked potential temporal dynamics reveal correlates of cognitive decline

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Diagnostic added value of electrical source imaging in presurgical evaluation of patients with epilepsy: A prospective study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Oscillatory connectivity as a diagnostic marker of dementia due to Alzheimer's disease

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Editorial: Need to find a signature of abnormal brain oscillations in task-specific focal dystonia

    Research output: Contribution to journalEditorialResearchpeer-review

  5. Automated EEG source imaging: A retrospective, blinded clinical validation study

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. What Should a Clinician Do When Spreading Depolarizations are Observed in a Patient?

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Which Spreading Depolarizations Are Deleterious To Brain Tissue?

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Diagnostic added value of electrical source imaging in presurgical evaluation of patients with epilepsy: A prospective study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Variation in the practice of tracheal intubation in Europe after traumatic brain injury: a prospective cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Brain Changes Induced by Electroconvulsive Therapy Are Broadly Distributed

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

OBJECTIVE: To investigate the effect of spatial sampling and of recording duration on the diagnostic yield of EEG for identification of interictal epileptiform discharges (IEDs). Previous studies demonstrated that high-density (HD) recordings increased accuracy of localization compared to low-density (LD) recordings.

METHODS: We have prospectively evaluated the effect of spatial sampling and of recording duration in patients who had short-term (ST) recordings with a HD array of 256 electrodes following long-term (LT) recordings with a LD array consisting of the standard IFCN array of 25 electrodes. IED clusters were identified in four datasets: LT-LD, ST-LD (spatially down-sampled to the standard IFCN array), ST-HD and a shortened (90 minutes) epoch of LT-LD.

RESULTS: Sixty consecutive patients were recruited. We identified 89 IED clusters totally. Two clusters were found by increasing spatial sampling from 25 to 256 electrodes. This modest increase was not statistically significant. Eight clusters were missed by reducing the recording duration to 90 minutes, as compared with the LT recordings (p = 0.003).

CONCLUSIONS: Recording duration is more important for the diagnostic yield of EEGs than increasing spatial sampling beyond the standard IFCN electrode array.

SIGNIFICANCE: The standard IFCN electrode array provides sufficient spatial sampling for identification of the IEDs.

Original languageEnglish
JournalClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Volume130
Issue number11
Pages (from-to)2060-2064
Number of pages5
ISSN1388-2457
DOIs
Publication statusPublished - Nov 2019

    Research areas

  • Diagnostic yield, Duration, EEG, High-density array, Interictal epileptiform discharges, Spatial sampling

ID: 58217105