Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Diagnostic Value of the Updated Diamond and Forrester Score to Predict Coronary Artery Disease in Patients with Acute-Onset Chest Pain

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. A Novel SCN5A Variant Associated with Abnormal Repolarization, Atrial Fibrillation, and Reversible Cardiomyopathy

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Leucocyte Telomere Length and Risk of Cardiovascular Disease in a Cohort of 1,397 Danish Men and Women

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Common genetic variants and risk of ischemic heart failure: an evaluation of a negative genetic study

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Women with coronary microvascular dysfunction and no obstructive coronary artery disease have reduced exercise capacity

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Coronary plaque composition assessed by cardiac computed tomography using adaptive Hounsfield unit thresholds

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Normal values of aortic dimensions assessed by multidetector computed tomography in the Copenhagen General Population Study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

OBJECTIVES: In the recently updated clinical guidelines from the European Society of Cardiology on the management of stable coronary artery disease (CAD), the updated Diamond Forrester score has been included as a pretest probability (PTP) score to select patients for further diagnostic testing. We investigated the validity of the new guidelines in a population of patients with acute-onset chest pain.

METHODS: We examined 527 consecutive patients with either an exercise-ECG stress test or single-photon emission computed tomography, and subsequently coronary computed tomography angiography (CCTA). We compared the diagnostic accuracy of PTP and stress testing assessed by the area under the receiver operating characteristic curve (AUC) to identify significant CAD, defined as at least 1 coronary artery branch with >70% diameter stenosis identified by CCTA.

RESULTS: The diagnostic accuracy of PTP was significantly higher than the stress test (AUC 0.80 vs. 0.69; p = 0.009), but the diagnostic accuracy of the combination of PTP and a stress test did not significantly increase when compared to PTP alone (AUC 0.86 vs. 0.80; p = 0.06).

CONCLUSIONS: PTP using the updated Diamond and Forrester Score is a very useful tool in risk-stratifying patients with acute-onset chest pain at a low-to-intermediate risk of having CAD. Adding a stress test to PTP does not appear to offer significant diagnostic benefit.

Original languageEnglish
JournalCardiology
Volume133
Issue number1
Pages (from-to)10-7
Number of pages8
ISSN0008-6312
DOIs
Publication statusPublished - 2016

ID: 45890522