Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital

Diagnostic Potential of Intracardiac Echocardiography in Patients with Suspected Prosthetic Valve Endocarditis

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Prognostic Value of Early Systolic Lengthening by Strain Imaging in Type 2 Diabetes

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Repeatability and Reproducibility of Neonatal Echocardiography: The Copenhagen Baby Heart Study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Exercise Hemodynamics After Aortic Valve Replacement for Severe Aortic Stenosis

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

BACKGROUND: The use of transthoracic and transesophageal echocardiography may be challenging in patients suspected of having prosthetic valve endocarditis (PVE). Intracardiac echocardiography (ICE) provides a new diagnostic tool in the examination of patients with PVE, yet few data on its use have been published.

METHODS: From January 2012 to December 2016, patients with suspected PVE and inconclusive findings on transthoracic and transesophageal echocardiography were further examined with ICE. Medical records were reviewed to assess clinical status, microbiologic etiology, echocardiography, antibiotic treatment, and surgical procedures. The modified Duke criteria were used to assess the diagnostic classification after ICE.

RESULTS: A total of 38 patients suspected of having PVE were included, of whom 17 patients had undergone transcatheter aortic heart valve implantation, 19 had surgically prosthetic valves, and two had tetralogy of Fallot with transcatheter pulmonary valves. After ICE, 19 patients were classified with definite PVE, and four patients were treated as having PVE because of overall clinical presentation. Of the 15 patients not treated for endocarditis after ICE, one patient had a relapse. Regarding procedural safety, no vascular complications occurred, whereas six of the patients (16%) had groin hematomas, which did not require intervention and had no sequelae.

CONCLUSIONS: Among patients with suspected PVE, ICE changed the diagnosis to definite PVE in half of the patients, with a low frequency of relapse among patients in whom PVE could not be confirmed by ICE. ICE may help guide clinicians in the duration of antibiotic treatment and surgical intervention in the treatment of patients with PVE.

Original languageEnglish
JournalJournal of the American Society of Echocardiography
Issue number12
Pages (from-to)1558-1564.e3
Publication statusPublished - Dec 2019

    Research areas

  • Diagnostic imaging, Infective endocarditis, Interventional cardiology, Intracardiac echocardiography, Prosthetic heart valve

ID: 58253091