Diagnosis-to-treatment interval is associated with outcomes in follicular lymphoma treated with immunochemotherapy

Prokop Vodička; Tarec Christoffer El-Galaly; V. Procházka; Christopher R. Flowers; Diego Villa; Caroline E. Dietrich; Lasse H. Jakobsen; Hervé Ghesquières; Michael R. Clausen; Robert Kridel; Chan Y. Cheah; Eliza A. Hawkes; Björn Wahlin; Maher K. Gandhi; Melissa C. Larson; Elliot J. Cahn; Jonathan W. Friedberg; Peter Martin; Dai Chihara; Jonathon B. Cohen; Thomas M. Habermann; Carla Casulo; Yucai Wang; Peter de Nully Brown; Eric Mou; David Belada; Andrea Janíková; Heidi Móciková; Richard Burack; Izidore S. Lossos; Brad S. Kahl; Karin E. Smedby; Laurie H. Sehn; Marek Trněný; James R. Cerhan; Matthew J. Maurer

doi:10.1182/blood.2026033090

Diagnosis-to-treatment interval is associated with outcomes in follicular lymphoma treated with immunochemotherapy

Prokop Vodička
, Tarec Christoffer El-Galaly
, V. Procházka
, Christopher R. Flowers
, Diego Villa
, Caroline E. Dietrich
, Lasse H. Jakobsen
, Hervé Ghesquières
, Michael R. Clausen
, Robert Kridel
, Chan Y. Cheah
, Eliza A. Hawkes
, Björn Wahlin
, Maher K. Gandhi
, Melissa C. Larson
, Elliot J. Cahn
, Jonathan W. Friedberg
, Peter Martin
, Dai Chihara
, Jonathon B. Cohen

Thomas M. Habermann, Carla Casulo, Yucai Wang, Peter de Nully Brown, Eric Mou, David Belada, Andrea Janíková, Heidi Móciková, Richard Burack, Izidore S. Lossos, Brad S. Kahl, Karin E. Smedby, Laurie H. Sehn, Marek Trněný, James R. Cerhan, Matthew J. Maurer^*

^*Corresponding author for this work

Department of Haematology

Abstract

A short diagnosis-to-treatment interval independently predicts inferior outcomes in follicular lymphoma. Using international discovery and validation cohorts, we demonstrate its prognostic value beyond established prognostic indices, with implications for risk stratification, clinical trial design, and interpretation.

Original language	English
Journal	Blood
Volume	147
Issue number	26
Pages (from-to)	3248-3252
Number of pages	5
ISSN	0006-4971
DOIs	https://doi.org/10.1182/blood.2026033090
Publication status	Published - 25 Jun 2026

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Vodička, P., El-Galaly, T. C., Procházka, V., Flowers, C. R., Villa, D., Dietrich, C. E., Jakobsen, L. H., Ghesquières, H., Clausen, M. R., Kridel, R., Cheah, C. Y., Hawkes, E. A., Wahlin, B., Gandhi, M. K., Larson, M. C., Cahn, E. J., Friedberg, J. W., Martin, P., Chihara, D., ... Maurer, M. J. (2026). Diagnosis-to-treatment interval is associated with outcomes in follicular lymphoma treated with immunochemotherapy. Blood, 147(26), 3248-3252. https://doi.org/10.1182/blood.2026033090

Vodička, P, El-Galaly, TC, Procházka, V, Flowers, CR, Villa, D, Dietrich, CE, Jakobsen, LH, Ghesquières, H, Clausen, MR, Kridel, R, Cheah, CY, Hawkes, EA, Wahlin, B, Gandhi, MK, Larson, MC, Cahn, EJ, Friedberg, JW, Martin, P, Chihara, D, Cohen, JB, Habermann, TM, Casulo, C, Wang, Y, de Nully Brown, P, Mou, E, Belada, D, Janíková, A, Móciková, H, Burack, R, Lossos, IS, Kahl, BS, Smedby, KE, Sehn, LH, Trněný, M, Cerhan, JR & Maurer, MJ 2026, 'Diagnosis-to-treatment interval is associated with outcomes in follicular lymphoma treated with immunochemotherapy', Blood, vol. 147, no. 26, pp. 3248-3252. https://doi.org/10.1182/blood.2026033090

@article{c3b0344826924891870fb3daa30242ca,

title = "Diagnosis-to-treatment interval is associated with outcomes in follicular lymphoma treated with immunochemotherapy",

abstract = "A short diagnosis-to-treatment interval independently predicts inferior outcomes in follicular lymphoma. Using international discovery and validation cohorts, we demonstrate its prognostic value beyond established prognostic indices, with implications for risk stratification, clinical trial design, and interpretation.",

author = "Prokop Vodi{\v c}ka and El-Galaly, \{Tarec Christoffer\} and V. Proch{\'a}zka and Flowers, \{Christopher R.\} and Diego Villa and Dietrich, \{Caroline E.\} and Jakobsen, \{Lasse H.\} and Herv{\'e} Ghesqui{\`e}res and Clausen, \{Michael R.\} and Robert Kridel and Cheah, \{Chan Y.\} and Hawkes, \{Eliza A.\} and Bj{\"o}rn Wahlin and Gandhi, \{Maher K.\} and Larson, \{Melissa C.\} and Cahn, \{Elliot J.\} and Friedberg, \{Jonathan W.\} and Peter Martin and Dai Chihara and Cohen, \{Jonathon B.\} and Habermann, \{Thomas M.\} and Carla Casulo and Yucai Wang and \{de Nully Brown\}, Peter and Eric Mou and David Belada and Andrea Jan{\'i}kov{\'a} and Heidi M{\'o}cikov{\'a} and Richard Burack and Lossos, \{Izidore S.\} and Kahl, \{Brad S.\} and Smedby, \{Karin E.\} and Sehn, \{Laurie H.\} and Marek Trn{\v e}n{\'y} and Cerhan, \{James R.\} and Maurer, \{Matthew J.\}",

note = "Publisher Copyright: {\textcopyright} 2026 American Society of Hematology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.",

year = "2026",

month = jun,

day = "25",

doi = "10.1182/blood.2026033090",

language = "English",

volume = "147",

pages = "3248--3252",

journal = "Blood",

issn = "0006-4971",

publisher = "Dove Medical Press Ltd",

number = "26",

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TY - JOUR

T1 - Diagnosis-to-treatment interval is associated with outcomes in follicular lymphoma treated with immunochemotherapy

AU - Vodička, Prokop

AU - El-Galaly, Tarec Christoffer

AU - Procházka, V.

AU - Flowers, Christopher R.

AU - Villa, Diego

AU - Dietrich, Caroline E.

AU - Jakobsen, Lasse H.

AU - Ghesquières, Hervé

AU - Clausen, Michael R.

AU - Kridel, Robert

AU - Cheah, Chan Y.

AU - Hawkes, Eliza A.

AU - Wahlin, Björn

AU - Gandhi, Maher K.

AU - Larson, Melissa C.

AU - Cahn, Elliot J.

AU - Friedberg, Jonathan W.

AU - Martin, Peter

AU - Chihara, Dai

AU - Cohen, Jonathon B.

AU - Habermann, Thomas M.

AU - Casulo, Carla

AU - Wang, Yucai

AU - de Nully Brown, Peter

AU - Mou, Eric

AU - Belada, David

AU - Janíková, Andrea

AU - Móciková, Heidi

AU - Burack, Richard

AU - Lossos, Izidore S.

AU - Kahl, Brad S.

AU - Smedby, Karin E.

AU - Sehn, Laurie H.

AU - Trněný, Marek

AU - Cerhan, James R.

AU - Maurer, Matthew J.

PY - 2026/6/25

Y1 - 2026/6/25

N2 - A short diagnosis-to-treatment interval independently predicts inferior outcomes in follicular lymphoma. Using international discovery and validation cohorts, we demonstrate its prognostic value beyond established prognostic indices, with implications for risk stratification, clinical trial design, and interpretation.

AB - A short diagnosis-to-treatment interval independently predicts inferior outcomes in follicular lymphoma. Using international discovery and validation cohorts, we demonstrate its prognostic value beyond established prognostic indices, with implications for risk stratification, clinical trial design, and interpretation.

UR - https://www.scopus.com/pages/publications/105039057981

U2 - 10.1182/blood.2026033090

DO - 10.1182/blood.2026033090

M3 - Letter

C2 - 41980013

AN - SCOPUS:105039057981

SN - 0006-4971

VL - 147

SP - 3248

EP - 3252

JO - Blood

JF - Blood

IS - 26

ER -

Diagnosis-to-treatment interval is associated with outcomes in follicular lymphoma treated with immunochemotherapy

Abstract

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