Dexrazoxane - A promising antidote in the treatment of accidental extravasation of anthracyclines

Jesper Næsted Jensen; Jørgen Lock-Andersen; Seppo W. Langer; Johannes Mejer

doi:10.1080/02844310310007791

Dexrazoxane - A promising antidote in the treatment of accidental extravasation of anthracyclines

Jesper Næsted Jensen^*, Jørgen Lock-Andersen, Seppo W. Langer, Johannes Mejer

^*Corresponding author for this work

40 Citations (Scopus)

Abstract

Accidental extravasation of chemotherapy containing anthracycline often causes mutilating complications as a result of extensive tissue necrosis. Treatment therefore consists of extensive surgical debridement. We present the case of a 41-year-old woman with breast cancer who experienced extravasation of epirubicin. She was treated with an intravenous infusion of dexrazoxane for three successive days and recovered without surgical treatment and only slightly dysaesthesia in the surrounding tissue. Although infusion of dexrazoxane for this indication is still experimental we consider it a promising treatment for patients who have accidental extravasation of anthracyclines.

Original language	English
Journal	Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery
Volume	37
Issue number	3
Pages (from-to)	174-175
Number of pages	2
ISSN	0284-4311
DOIs	https://doi.org/10.1080/02844310310007791
Publication status	Published - 2003
Externally published	Yes

Keywords

Anthracyclines
Breast cancer
Complication
Dexrazoxane
Extravasation

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10.1080/02844310310007791

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Dexrazoxane - A promising antidote in the treatment of accidental extravasation of anthracyclines. / Jensen, Jesper Næsted; Lock-Andersen, Jørgen; Langer, Seppo W. et al.
In: Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, Vol. 37, No. 3, 2003, p. 174-175.

Research output: Contribution to journal › Journal article › Research › peer-review

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AU - Mejer, Johannes

PY - 2003

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KW - Complication

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KW - Extravasation

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Dexrazoxane - A promising antidote in the treatment of accidental extravasation of anthracyclines

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Keywords

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